Transcripts for sweet and bitter taste receptors and the gustatory G proteins, α-gustducin and α-transducin, are expressed by the oral cavity and the gastrointestinal (GI) mucosa. This study evaluated: 1) distribution of α-transducin in the pig GI tract; 2) type of cells expressing α-transducin (chromogranin-A, gastrin/cholecystokinin, somatostatin, villin) 3) relationship between α-transducin cells and enteric nerves. The presence of α-transducin-IR in enteroendocrine cells supports an active chemosensory machinery in the GI mucosa and that taste signalling molecules contribute to luminal chemosensing. These mechanisms may occur via neuro-endocrine cross-talk activating digestive or protective reflex pathways (e.g. vomiting or food aversion).
Titolo: | Espressione dell’ α-transducina, una molecola della chemorecezione, in cellule endocrine e non endocrine del tratto gastrointestinale di suino. | |
Autore/i: | CLAVENZANI, PAOLO; DE GIORGIO, ROBERTO; MAZZONI, MAURIZIO; CHIOCCHETTI, ROBERTO; BARBARA, GIOVANNI; LALATTA COSTERBOSA, GIOVANNA; RUSSO D.; STERNINI C. | |
Autore/i Unibo: | ||
Anno: | 2008 | |
Titolo del libro: | LXII Convegno Nazionale della Società Italiana delle Scienze Veterinarie | |
Pagina iniziale: | 5 | |
Pagina finale: | 6 | |
Abstract: | Transcripts for sweet and bitter taste receptors and the gustatory G proteins, α-gustducin and α-transducin, are expressed by the oral cavity and the gastrointestinal (GI) mucosa. This study evaluated: 1) distribution of α-transducin in the pig GI tract; 2) type of cells expressing α-transducin (chromogranin-A, gastrin/cholecystokinin, somatostatin, villin) 3) relationship between α-transducin cells and enteric nerves. The presence of α-transducin-IR in enteroendocrine cells supports an active chemosensory machinery in the GI mucosa and that taste signalling molecules contribute to luminal chemosensing. These mechanisms may occur via neuro-endocrine cross-talk activating digestive or protective reflex pathways (e.g. vomiting or food aversion). | |
Data prodotto definitivo in UGOV: | 26-nov-2008 | |
Data stato definitivo: | 14-giu-2016 | |
Appare nelle tipologie: | 4.02 Riassunto (Abstract) |