Tendon injuries represent an unsolved clinical need. Electrospun bundles using blends of poly-L-lactic acid (PLLA) and collagen (Coll) in different percentages were prepared by an ‘ad hoc’ crosslinking system to increase the mechanical properties and reduce the loss of collagen after ageing in a physiological environment. The mechanical properties and cell proliferation were tested. High-resolution x- ray tomography was also performed to investigate the morphologyof the bundles.
Fabrication and characterization of electrospun scaffolds for tendon reconstruction
A. Sensini;M. L. Focarete;C. Gualandi;A. Zucchelli;L. Cristofolini
2017
Abstract
Tendon injuries represent an unsolved clinical need. Electrospun bundles using blends of poly-L-lactic acid (PLLA) and collagen (Coll) in different percentages were prepared by an ‘ad hoc’ crosslinking system to increase the mechanical properties and reduce the loss of collagen after ageing in a physiological environment. The mechanical properties and cell proliferation were tested. High-resolution x- ray tomography was also performed to investigate the morphologyof the bundles.File in questo prodotto:
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