Intrahepatic cholangiocarcinoma is an aggressive tumor usually discovered at an advanced stage. Surgical resection is the treatment of choice but less than 50% of patients may receive curative resection. In almost 70% of patients, extended hepatectomy with vascular resection and/or bile duct resection are required to achieve a negative margin. Overall 5-year survival is around 30%. Prognosis is mainly based on tumor factors such as size, number, lymph node or vascular invasion and surgical margin. The main sites of recurrence are the liver, peritoneum and lymph nodes. In patients with liver-only recurrence, re-resection should always be considered.
Intrahepatic cholangiocarcinoma is an aggressive tumor usually discovered at an advanced stage. Surgical resection is the treatment of choice but less than 50% of patients may receive curative resection. In almost 70% of patients, extended hepatectomy with vascular resection and/or bile duct resection are required to achieve a negative margin. Overall 5-year survival is around 30%. Prognosis is mainly based on tumor factors such as size, number, lymph node or vascular invasion and surgical margin. The main sites of recurrence are the liver, peritoneum and lymph nodes. In patients with liver-only recurrence, re-resection should always be considered.
Ercolani, G., Cucchetti, A., Cucchi, M., Cescon, M., Del Gaudio, M., Ravaioli, M., et al. (2015). Surgical treatment for intrahepatic cholangiocarcinoma. New York : Nova Science Publishers, Inc..
Surgical treatment for intrahepatic cholangiocarcinoma
ERCOLANI, GIORGIO;CUCCHETTI, ALESSANDRO;CUCCHI, MICHELE;CESCON, MATTEO;DEL GAUDIO, MASSIMO;RAVAIOLI, MATTEO;PINNA, ANTONIO DANIELE
2015
Abstract
Intrahepatic cholangiocarcinoma is an aggressive tumor usually discovered at an advanced stage. Surgical resection is the treatment of choice but less than 50% of patients may receive curative resection. In almost 70% of patients, extended hepatectomy with vascular resection and/or bile duct resection are required to achieve a negative margin. Overall 5-year survival is around 30%. Prognosis is mainly based on tumor factors such as size, number, lymph node or vascular invasion and surgical margin. The main sites of recurrence are the liver, peritoneum and lymph nodes. In patients with liver-only recurrence, re-resection should always be considered.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
