Due to its similarity with the mineral phase of bone and to its high biocompatibility and bioactivity, synthetic hydroxyapatite (HA) is widely employed for the preparation of biomaterials for hard tissue substitution/repair. One of the most relevant peculiarities of biological apatites is the associated presence of a number of foreign ions, which play an essential, dose-dependent, role on the properties of mineralized tissues. Substitution with biologically relevant ions can improve the biological performance of HA-based materials. This chapter reviews the main characteristics of biological apatites, with particular focus on the associated foreign ions, and of synthetic HA, with particular emphasis on the structural and chemical modifications induced by ionic substitution.
Ion Substitution in Biological and Synthetic Apatites / Adriana Bigi; Elisa Boanini; Massimo Gazzano. - STAMPA. - (2016), pp. 235-266. [10.1016/B978-1-78242-338-6.00008-9]
Ion Substitution in Biological and Synthetic Apatites
BIGI, ADRIANA;BOANINI, ELISA;
2016
Abstract
Due to its similarity with the mineral phase of bone and to its high biocompatibility and bioactivity, synthetic hydroxyapatite (HA) is widely employed for the preparation of biomaterials for hard tissue substitution/repair. One of the most relevant peculiarities of biological apatites is the associated presence of a number of foreign ions, which play an essential, dose-dependent, role on the properties of mineralized tissues. Substitution with biologically relevant ions can improve the biological performance of HA-based materials. This chapter reviews the main characteristics of biological apatites, with particular focus on the associated foreign ions, and of synthetic HA, with particular emphasis on the structural and chemical modifications induced by ionic substitution.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
