Thermodynamics of sodium naproxen salt aqueous solutions at 20-45°C

To control quality of drug compounds it needs information about key physico-chemical parameters both of substances and solutions. At other side, aqueous solutions are interesting as systems, which model intercellular pathways of drug delivery. The wide set of thermodynamic characteristics gives opportunity to characterize the state of drug molecules in the outlined systems. This fact allows understanding and analyzing forces of passive transport process. The present work is a continuation of our previous investigations devoted to thermodynamics of aqueous solution of nonsteroidal anti-inflammatory drugs of ionic nature: the solution/dilution enthalpies of naproxen sodium salt in water at different temperatures are here presented and discussed. The analysis of thermodynamic characteristic of the solution from concentration and temepraturs have been carried out and discussed.