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EnglishEvidence in the literature reports motility abnormalities in patients with inflammatory bowel disorders. Many of the symptoms reported by patients derive from alteration in gut physiology. The mechanisms of this dysmotility are uncertain but different factors, either direct or indirect, of muscles and nerves can produce alteration of gut functions through the involvement of endocrine and neural networks. We can summarize that entry of new ingesta into the colon during the postprandial period stimulates enteric mechanisms to initiate an excessive number of both high and low-amplitude propagating contractions. The decreased contractile function of the smooth muscle further helps acceleration of propulsion by decreasing segmental contractions and allowing forward movement of the colonic contents without impediments. The anorectal region is characterized by increased sensitivity to distension and reduced compliance
| Titolo: | Colonic and anorectal motility in inflammatory bowel disease | |
| Autore/i: | SALVIOLI, BEATRICE; BAZZOCCHI, GABRIELE | |
| Autore/i Unibo: | ||
| Anno: | 2006 | |
| Titolo del libro: | Inflammatory Bowel Disease and Familial Adenomatous Polyposis: Clinical Management and Patients' Quality of Life | |
| Pagina iniziale: | 51 | |
| Pagina finale: | 59 | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/88-470-0434-9_6 | |
| Abstract: | Evidence in the literature reports motility abnormalities in patients with inflammatory bowel disorders. Many of the symptoms reported by patients derive from alteration in gut physiology. The mechanisms of this dysmotility are uncertain but different factors, either direct or indirect, of muscles and nerves can produce alteration of gut functions through the involvement of endocrine and neural networks. We can summarize that entry of new ingesta into the colon during the postprandial period stimulates enteric mechanisms to initiate an excessive number of both high and low-amplitude propagating contractions. The decreased contractile function of the smooth muscle further helps acceleration of propulsion by decreasing segmental contractions and allowing forward movement of the colonic contents without impediments. The anorectal region is characterized by increased sensitivity to distension and reduced compliance | |
| Data prodotto definitivo in UGOV: | 27-feb-2007 | |
| Appare nelle tipologie: | 2.01 Capitolo / saggio in libro |
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