The use of biomaterials for cartilage repair has strongly increased in the last decade, due to promising results obtained with the development of new therapeutic options for treatment of articular cartilage lesions. A good biomaterial for cartilage repair should ideally be: 1. An off-the-shelf graft in a one-step surgical procedure. 2. From a surgical standpoint, it should be inserted under minimally invasive conditions. 3. Should be a graded biomimetic osteochondral scaffold, promoting by itself bone and cartilage tissue restoration by inducing selective bone marrow stem cell differentiation in osteogenic and chondrogenic lineages.
Kon E, Delcogliano M, Di Martino A, Filardo G, Niceforo G, Zarbà V, et al. (2010). Biomaterials and cartilage repair. LONDON : DJO Publication.
Biomaterials and cartilage repair
KON, ELIZAVETA;FILARDO, GIUSEPPE;ZAFFAGNINI, STEFANO;MARCACCI, MAURILIO
2010
Abstract
The use of biomaterials for cartilage repair has strongly increased in the last decade, due to promising results obtained with the development of new therapeutic options for treatment of articular cartilage lesions. A good biomaterial for cartilage repair should ideally be: 1. An off-the-shelf graft in a one-step surgical procedure. 2. From a surgical standpoint, it should be inserted under minimally invasive conditions. 3. Should be a graded biomimetic osteochondral scaffold, promoting by itself bone and cartilage tissue restoration by inducing selective bone marrow stem cell differentiation in osteogenic and chondrogenic lineages.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
