Pyrethroids are synthetic insecticides possessing greater insecticidal potency and enhanced photostability than plant-derived pyrethrins. Thanks to their low mammalian toxicity and biodegradability, they emerged as a replacement for DDT since the late ’60. The demand for pyrethoids is increasing, also due to the upgraded agriculture technologies of “emerging countries” such as China. Resmethrin was one of the first members of the pyrethroid family to be used. Available preparations of 3 pose an heavy burden on the environment. We present here an alternative route to 1, that avoids the use of 3. A comparative quantitative assessment of the “greenness” of the process will also be shown. Among the several metrics available, we chose to use EATOS ( ) which takes into account both the mass economy and the environmental impact of the materials involved. The assessment was made using a freeware software, available from the authors (6), that produces readily comparable charts.
P. Righi, G. Rosini, V. Borzatta (2006). GREEN METRICS: COMPARATIVE ASSESSMENT OF AN ALTERNATIVE SYNTHESIS OF 5-BENZYL-3-FURFURYL ALCOHOL, A KEY INTERMEDIATE FOR THE PRODUCTION OF RESMETHRINS. VENEZIA : INCA - Consorzio Int. Chimica per l'Ambiente.
GREEN METRICS: COMPARATIVE ASSESSMENT OF AN ALTERNATIVE SYNTHESIS OF 5-BENZYL-3-FURFURYL ALCOHOL, A KEY INTERMEDIATE FOR THE PRODUCTION OF RESMETHRINS
RIGHI, PAOLO;ROSINI, GOFFREDO;
2006
Abstract
Pyrethroids are synthetic insecticides possessing greater insecticidal potency and enhanced photostability than plant-derived pyrethrins. Thanks to their low mammalian toxicity and biodegradability, they emerged as a replacement for DDT since the late ’60. The demand for pyrethoids is increasing, also due to the upgraded agriculture technologies of “emerging countries” such as China. Resmethrin was one of the first members of the pyrethroid family to be used. Available preparations of 3 pose an heavy burden on the environment. We present here an alternative route to 1, that avoids the use of 3. A comparative quantitative assessment of the “greenness” of the process will also be shown. Among the several metrics available, we chose to use EATOS ( ) which takes into account both the mass economy and the environmental impact of the materials involved. The assessment was made using a freeware software, available from the authors (6), that produces readily comparable charts.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
