The present invention relates to rifaximin polymorphic forms a, b and g, the processes for their prepn. and the use thereof in the manuf. of medicinal prepns. for the oral or topical route. A hydroalcoholic suspension of 5 g of rifaximin g was heated at 40 Deg for 24 h, the suspension was then filtered and the solid was washed with water, then dried under vacuum at room temp. until const. wt. 4 g of rifaximin was obtained, showing a powder X-ray diffractogram corresponding to that of the polymorphic form a and a water content equal to 2.6%.

Viscomi G.C., Campana M., Braga D., Confortini D., Cannata V., Righi P., et al. (2005). Polymorphic forms of rifaximin, processes for their production and uses thereof.

Polymorphic forms of rifaximin, processes for their production and uses thereof

BRAGA, DARIO;RIGHI, PAOLO;ROSINI, GOFFREDO
2005

Abstract

The present invention relates to rifaximin polymorphic forms a, b and g, the processes for their prepn. and the use thereof in the manuf. of medicinal prepns. for the oral or topical route. A hydroalcoholic suspension of 5 g of rifaximin g was heated at 40 Deg for 24 h, the suspension was then filtered and the solid was washed with water, then dried under vacuum at room temp. until const. wt. 4 g of rifaximin was obtained, showing a powder X-ray diffractogram corresponding to that of the polymorphic form a and a water content equal to 2.6%.
2005
2005-135651
Viscomi G.C., Campana M., Braga D., Confortini D., Cannata V., Righi P., et al. (2005). Polymorphic forms of rifaximin, processes for their production and uses thereof.
Viscomi G.C.; Campana M.; Braga D.; Confortini D.; Cannata V.; Righi P.; Rosini G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/26661
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