The present invention relates to a process for producing polyhydroxyalkanoate oligomers and/or polymers of reduced molecular weight, which comprises reacting at least one polyhydroxyalkanoate (PHA) with at least one carbonate salt at a temperature of from 50 DEG C to 300 DEG C, preferably from 120 DEG C to 200 DEG C. The above reaction allows a controlled degradation of the PHA chains which yields oligomers and/or polymers having a controlled molecular weight, which can be modulated in view of the specific application for which the oligomers and/or polymers are intended. Moreover, during the reaction carbon dioxide evolves which produces a foamed material which can be easily processed on an industrial scale.; Additionally, the above oligomers and/or polymers, having an end-group bearing a double bond C=C, particularly a crotonate end-group for PHB, can be subjected to subsequent modifications to obtain a wide variety of functional end-groups, for instance carboxyl, carboxylate, hydroxyl, dihydroxyl, oxirane ring, halogen atom. Moreover, the low molecular weight PHAs may be used in the area of controlled delivery systems in agro-chemistry, in the cosmetic industry, in medicine in the form of nano- or microspheres, in household products and in coating systems.

PROCESS FOR CONTROLLED DEGRADATION OF POLYHYDROXYALKANOATES AND PRODUCTS OBTAINABLE THEREFROM

SCANDOLA, MARIASTELLA;MAZZOCCHETTI, LAURA;FOCARETE, MARIA LETIZIA;
2008

Abstract

The present invention relates to a process for producing polyhydroxyalkanoate oligomers and/or polymers of reduced molecular weight, which comprises reacting at least one polyhydroxyalkanoate (PHA) with at least one carbonate salt at a temperature of from 50 DEG C to 300 DEG C, preferably from 120 DEG C to 200 DEG C. The above reaction allows a controlled degradation of the PHA chains which yields oligomers and/or polymers having a controlled molecular weight, which can be modulated in view of the specific application for which the oligomers and/or polymers are intended. Moreover, during the reaction carbon dioxide evolves which produces a foamed material which can be easily processed on an industrial scale.; Additionally, the above oligomers and/or polymers, having an end-group bearing a double bond C=C, particularly a crotonate end-group for PHB, can be subjected to subsequent modifications to obtain a wide variety of functional end-groups, for instance carboxyl, carboxylate, hydroxyl, dihydroxyl, oxirane ring, halogen atom. Moreover, the low molecular weight PHAs may be used in the area of controlled delivery systems in agro-chemistry, in the cosmetic industry, in medicine in the form of nano- or microspheres, in household products and in coating systems.
WO2010044112 (A1) ― 2010-04-22
SCANDOLA MARIASTELLA; MAZZOCCHETTI LAURA; FOCARETE MARIA LETIZIA; KAWALEC MICHAL; KURCOK PIOTR; ADAMUS GRAZYNA; KOWALCZUK MAREK
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/213635
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