3,6-Disubstituted-1,2-diaminocycloexenes 5-7 are prepared by ring closing metathesis (RCM) reactions, catalysed by Grubbs’ ruthenium carbenecomplexes, of 4,5-diammino-3,6-disubstituted-1,7-octadienes 2, in turn available by the addition of allylic zinc reagents to the chiral diimine 1, by analogy with the previously described preparation of compounds 31and 42. Removal of the chiral auxiliary by hydrogenolysis affords the corresponding primary 1,2-diaminocyclohexanes.

STEREOSELECTIVE SYNTHESIS OF 3,6-DISUBSTITUTED 1,2-DIAMINOCYCLOHEXANES BY RING CLOSING METATHESIS REACTIONS / C. Fiorelli; D. Savoia. - STAMPA. - (2004), pp. P83-P83. (Intervento presentato al convegno III Euchem Conference, Nitrogen ligands in organometallic chemistry and homogeneous catalysis tenutosi a Camerino nel 8-12 settembre 2004).

STEREOSELECTIVE SYNTHESIS OF 3,6-DISUBSTITUTED 1,2-DIAMINOCYCLOHEXANES BY RING CLOSING METATHESIS REACTIONS

FIORELLI, CLAUDIO;SAVOIA, DIEGO
2004

Abstract

3,6-Disubstituted-1,2-diaminocycloexenes 5-7 are prepared by ring closing metathesis (RCM) reactions, catalysed by Grubbs’ ruthenium carbenecomplexes, of 4,5-diammino-3,6-disubstituted-1,7-octadienes 2, in turn available by the addition of allylic zinc reagents to the chiral diimine 1, by analogy with the previously described preparation of compounds 31and 42. Removal of the chiral auxiliary by hydrogenolysis affords the corresponding primary 1,2-diaminocyclohexanes.
2004
Nitrogen ligands in organometallic chemistry and homogeneous catalysis
P83
P83
STEREOSELECTIVE SYNTHESIS OF 3,6-DISUBSTITUTED 1,2-DIAMINOCYCLOHEXANES BY RING CLOSING METATHESIS REACTIONS / C. Fiorelli; D. Savoia. - STAMPA. - (2004), pp. P83-P83. (Intervento presentato al convegno III Euchem Conference, Nitrogen ligands in organometallic chemistry and homogeneous catalysis tenutosi a Camerino nel 8-12 settembre 2004).
C. Fiorelli; D. Savoia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/15977
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