Tandem repeats constitute a consistent fraction of eukaryotic genomes and are given by monomers or gene clusters repeated in a head-to-tail direction. Main examples are represented by microsatellites, minisatellites, satellites, rDNA genes, and protein-coding genes. Tandem repeats dynamics is mainly due to nonreciprocal genomic turnover mechanisms, leading to copy number variation. They differently impact on genome evolution and some of them appear clearly linked to human diseases and are applied for DNA fingerprinting.
Tandem Repeats
MANTOVANI, BARBARA
2013
Abstract
Tandem repeats constitute a consistent fraction of eukaryotic genomes and are given by monomers or gene clusters repeated in a head-to-tail direction. Main examples are represented by microsatellites, minisatellites, satellites, rDNA genes, and protein-coding genes. Tandem repeats dynamics is mainly due to nonreciprocal genomic turnover mechanisms, leading to copy number variation. They differently impact on genome evolution and some of them appear clearly linked to human diseases and are applied for DNA fingerprinting.File in questo prodotto:
Eventuali allegati, non sono esposti
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
