Somatostatin receptor PET-CThemploys positron emitting tracers (68Ga-DOTA-peptides) that specifically bind to somatostatin receptors (ssr) expressed on tumor cell surface and has been used mainly for the assessment of neuroendocrine tumors (NETs). NETs derive from neuroendocrine cells widely dispersed in the human body and present an increased expression of ssr, particularly of ssr2. 68Ga-DOTA-peptides are very accurate for the assessment of well-differentiated NETs, since being slow-growing tumors, they are not clearly visualized on 18F-FDG PET-CT scans.
Ambrosini V, Castellucci P, Montini GC, Fanti S (2009). Somatostatin Receptor PET/CT. BERLIN HEIDELBERG : Springer Berlin Heidelberg [10.1007/978-3-540-93909-2_7].
Somatostatin Receptor PET/CT
AMBROSINI, VALENTINA;FANTI, STEFANO
2009
Abstract
Somatostatin receptor PET-CThemploys positron emitting tracers (68Ga-DOTA-peptides) that specifically bind to somatostatin receptors (ssr) expressed on tumor cell surface and has been used mainly for the assessment of neuroendocrine tumors (NETs). NETs derive from neuroendocrine cells widely dispersed in the human body and present an increased expression of ssr, particularly of ssr2. 68Ga-DOTA-peptides are very accurate for the assessment of well-differentiated NETs, since being slow-growing tumors, they are not clearly visualized on 18F-FDG PET-CT scans.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
