ABSTRACT Infection is broadly recognized as one of the most critical and devastating complications associated with the use of biomaterials, particularly in orthopaedic prosthesis surgery . The idea of combining biomaterials with antimicrobial substances for prophylaxis of infections through local delivery was first developed in dentistry and then the combination of antibiotic-cement was proposed also in orthopaedic surgery. Various prophylaxis measures or antimicrobial treatments are analysed and their different efficacies are considered. Different strategies in designing and using infection-resistant and anti-infective biomaterials are presented and discussed.

Implant infections and infection resistant materials

MONTANARO, LUCIO;ARCIOLA, CARLA RENATA
2012

Abstract

ABSTRACT Infection is broadly recognized as one of the most critical and devastating complications associated with the use of biomaterials, particularly in orthopaedic prosthesis surgery . The idea of combining biomaterials with antimicrobial substances for prophylaxis of infections through local delivery was first developed in dentistry and then the combination of antibiotic-cement was proposed also in orthopaedic surgery. Various prophylaxis measures or antimicrobial treatments are analysed and their different efficacies are considered. Different strategies in designing and using infection-resistant and anti-infective biomaterials are presented and discussed.
2012
Degradation of Implant Materials
347
358
Campoccia D; Montanaro L; Arciola CR
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/124029
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