ABSTRACT Infection is broadly recognized as one of the most critical and devastating complications associated with the use of biomaterials, particularly in orthopaedic prosthesis surgery . The idea of combining biomaterials with antimicrobial substances for prophylaxis of infections through local delivery was first developed in dentistry and then the combination of antibiotic-cement was proposed also in orthopaedic surgery. Various prophylaxis measures or antimicrobial treatments are analysed and their different efficacies are considered. Different strategies in designing and using infection-resistant and anti-infective biomaterials are presented and discussed.
Campoccia D, Montanaro L, Arciola CR (2012). Implant infections and infection resistant materials. NEW YORK HEIDELBERG DORDRECHT : Springer [10.1007/978-1-4614-3942-4_13].
Implant infections and infection resistant materials
MONTANARO, LUCIO;ARCIOLA, CARLA RENATA
2012
Abstract
ABSTRACT Infection is broadly recognized as one of the most critical and devastating complications associated with the use of biomaterials, particularly in orthopaedic prosthesis surgery . The idea of combining biomaterials with antimicrobial substances for prophylaxis of infections through local delivery was first developed in dentistry and then the combination of antibiotic-cement was proposed also in orthopaedic surgery. Various prophylaxis measures or antimicrobial treatments are analysed and their different efficacies are considered. Different strategies in designing and using infection-resistant and anti-infective biomaterials are presented and discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
