Elevated plasma total homocysteine concentrations (tHcy) are common in the elderly and may be a risk factor for dementia. In an elderly population, we examined the relationship between plasma tHcy and the Mini Mental State Examination (MMSE), a commonly used screening measure of cognitive impairment. Fasting plasma tHcy concentrations were measured in 650 healthy, cognitively normal Italian community-dwellers aged >= 65. Shortly, we found that hyperhocysteinemia has an independent association with concurrent cognitive impairment as measured by MMSE in healthy community-dwellers.
RAVAGLIA G, FORTI P, MAIOLI F, MUSCARI A, SACCHETTI L, ARNONE G, et al. (2005). Homocysteine and cognitive function in healthy elderly Italian community dwellers. NEW YORK : Springer Publishing Company.
Homocysteine and cognitive function in healthy elderly Italian community dwellers
RAVAGLIA, GIOVANNI;FORTI, PAOLA;MUSCARI, ANTONIO;MARIANI, ERMINIA
2005
Abstract
Elevated plasma total homocysteine concentrations (tHcy) are common in the elderly and may be a risk factor for dementia. In an elderly population, we examined the relationship between plasma tHcy and the Mini Mental State Examination (MMSE), a commonly used screening measure of cognitive impairment. Fasting plasma tHcy concentrations were measured in 650 healthy, cognitively normal Italian community-dwellers aged >= 65. Shortly, we found that hyperhocysteinemia has an independent association with concurrent cognitive impairment as measured by MMSE in healthy community-dwellers.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
