CRIS Current Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishBackground and aims: Apnoea of prematurity (AOP) is a frequent clinical issue in the management of preterm infants; its relationship with gastroesophageal reflux (GER) is widely debated. In a previous study we highlighted an increase of the frequency of AOP after GER (GER-induced AOP). The aim of the present study is to evaluate the effect of an amylopectin-thickened formula specifically designed for preterm infants on AOP and on GER-induced AOP. Materials and Methods: Eighteen preterm infants (gestational age < 32 weeks) with recurrent apnoeas underwent a six-hours simultaneous and synchronized recording of polysomnography and pH-impedance monitoring (pH-MII). Each oral/nasal flow cessation lasting at least 5 seconds was considered as apnoea. Apnoeas detected within 30 seconds after the onset of GER were defined as GER-induced. Each patient received 2 meals, one of preterm formula (PF) and the other of a thickened formula specifically designed to satisfy preterm infants' nutritional needs (TPF). AOP and GER-induced AOP detected after PF and TPF meals were compared. Results: One-hundred-twenty-seven apnoeas were recorded after TPF (mean 5/patient, range 0-21), whereas 118 apnoeas were recorded after PF (mean 4.5, range 0-27). A lower number of GER-induced AOP was detected after TPF meals (3 vs 7 after PF meals). Conclusions: Preliminary results of the present study show that a thickened formula specifically designed for preterm infants is ineffective in reducing the total number of AOP, while it could be beneficial on GER-induced AOP. Further data from a larger population are needed to confirm these results.
| Titolo: | Effect of a thickened formula specifically designed for preterm infants on apnoeas induced by gastroesophageal reflux | |
| Autore/i: | M. Spizzichino; CORVAGLIA, LUIGI TOMMASO; ZAMA, DANIELE; BATTISTINI, BARBARA; E. Legnani; FALDELLA, GIACOMO | |
| Autore/i Unibo: | ||
| Anno: | 2011 | |
| Rivista: | ||
| Titolo del libro: | Pediatric Research (Supplement 5s) | |
| Pagina iniziale: | 785 | |
| Pagina finale: | 785 | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1038/pr.2011.1010 | |
| Abstract: | Background and aims: Apnoea of prematurity (AOP) is a frequent clinical issue in the management of preterm infants; its relationship with gastroesophageal reflux (GER) is widely debated. In a previous study we highlighted an increase of the frequency of AOP after GER (GER-induced AOP). The aim of the present study is to evaluate the effect of an amylopectin-thickened formula specifically designed for preterm infants on AOP and on GER-induced AOP. Materials and Methods: Eighteen preterm infants (gestational age < 32 weeks) with recurrent apnoeas underwent a six-hours simultaneous and synchronized recording of polysomnography and pH-impedance monitoring (pH-MII). Each oral/nasal flow cessation lasting at least 5 seconds was considered as apnoea. Apnoeas detected within 30 seconds after the onset of GER were defined as GER-induced. Each patient received 2 meals, one of preterm formula (PF) and the other of a thickened formula specifically designed to satisfy preterm infants' nutritional needs (TPF). AOP and GER-induced AOP detected after PF and TPF meals were compared. Results: One-hundred-twenty-seven apnoeas were recorded after TPF (mean 5/patient, range 0-21), whereas 118 apnoeas were recorded after PF (mean 4.5, range 0-27). A lower number of GER-induced AOP was detected after TPF meals (3 vs 7 after PF meals). Conclusions: Preliminary results of the present study show that a thickened formula specifically designed for preterm infants is ineffective in reducing the total number of AOP, while it could be beneficial on GER-induced AOP. Further data from a larger population are needed to confirm these results. | |
| Data prodotto definitivo in UGOV: | 24-giu-2013 | |
| Data stato definitivo: | 24-dic-2015 | |
| Appare nelle tipologie: | 4.02 Riassunto (Abstract) |
File in questo prodotto:
Copyright © 2022