A diagnostic device suitable for Parvovirus B19 genotyping and quantitative DNA detection was developed, based on hybridization with immobilized oligonucleotide probes and chemiluminescence detection. The microfluidic chamber was directly coupled with a CCD sensor in a “contact” imaging configuration to obtain a portable device suitable for point-of-care applications.
Point-Of-Care Parvovirus B19 detection and genotyping based on microfluidics and chemiluminescence “contact” imaging detection.
DOLCI, LUISA STELLA;MIRASOLI, MARA;BURAGINA, ANGELA;GUARDIGLI, MASSIMO;RODA, ALDO;BONVICINI, FRANCESCA;DI FURIO, FRANCESCA
2011
Abstract
A diagnostic device suitable for Parvovirus B19 genotyping and quantitative DNA detection was developed, based on hybridization with immobilized oligonucleotide probes and chemiluminescence detection. The microfluidic chamber was directly coupled with a CCD sensor in a “contact” imaging configuration to obtain a portable device suitable for point-of-care applications.File in questo prodotto:
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