Hypertension (HBP) is associated with vascular inflammatory responses and is a major risk factor in development of atherosclerosis but molecular and cellular mechanisms are unclear. Inflammatory cell infiltration and oxidative stress in vascular walls contribute to the pathogenesis of HBP in experimental animals, thus, controlling chemokines production is important to regulate inflammatory reactions in hypertensive arterial walls. The aim of this study is to evaluate IP-10, inflammatory chemokine, serum concentration in a free living human population with different leves of cardiovascular diseases (CVD) risk.
31. Rosticci M., Cristino S., Baldi E., Dormi A., Borghi C (2009). Expression of interferon inducible protein-10 (IP-10) in free living population: association with CVD risk..
Expression of interferon inducible protein-10 (IP-10) in free living population: association with CVD risk.
ROSTICCI, MARTINA;CRISTINO, SANDRA;DORMI, ADA;BORGHI, CLAUDIO
2009
Abstract
Hypertension (HBP) is associated with vascular inflammatory responses and is a major risk factor in development of atherosclerosis but molecular and cellular mechanisms are unclear. Inflammatory cell infiltration and oxidative stress in vascular walls contribute to the pathogenesis of HBP in experimental animals, thus, controlling chemokines production is important to regulate inflammatory reactions in hypertensive arterial walls. The aim of this study is to evaluate IP-10, inflammatory chemokine, serum concentration in a free living human population with different leves of cardiovascular diseases (CVD) risk.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
