The interest towards new elastomeric materials with low elastic modulus (E), suitable for soft tissue engineering applications (E in the range 0.1-100 MPa, according to the specific native tissue), and with controllable degradation profiles has increased significantly in the last decade. In this work new biomaterials exhibiting elastomeric properties are synthesized through reactive blending. Multiblock poly(butylene-b-triethylene succinate) copolymers (P(BSTES)) are presented and their solid-state properties, hydrolytic degradation profiles and biocompatibility are investigated and correlated with copolymer molecular structure.
New multiblock copolyesters from reactive blending for soft tissue engineering / C. Gualandi; M. Soccio; E. Saino; M.L. Focarete; N. Lotti; A. Munari; L. Visai. - STAMPA. - (2011), pp. 32-32. (Intervento presentato al convegno Congresso Nazionale SIB 2011 tenutosi a Bari (Italy) nel 23-25 Maggio 2011).
New multiblock copolyesters from reactive blending for soft tissue engineering
GUALANDI, CHIARA;SOCCIO, MICHELINA;FOCARETE, MARIA LETIZIA;LOTTI, NADIA;MUNARI, ANDREA;
2011
Abstract
The interest towards new elastomeric materials with low elastic modulus (E), suitable for soft tissue engineering applications (E in the range 0.1-100 MPa, according to the specific native tissue), and with controllable degradation profiles has increased significantly in the last decade. In this work new biomaterials exhibiting elastomeric properties are synthesized through reactive blending. Multiblock poly(butylene-b-triethylene succinate) copolymers (P(BSTES)) are presented and their solid-state properties, hydrolytic degradation profiles and biocompatibility are investigated and correlated with copolymer molecular structure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
