Materials with low elastic modulus (E) are expected to satisfy the required compliance of soft tissue engineering applications (E in the range 0.1-100 MPa, according to the specific tissue). Accordingly, the interest towards new elastomeric materials with controllable degradation profiles has increased significantly in the last decade3. In this work we propose reactive blending as a simple and versatile solvent-free synthetic approach to produce new biomaterials exhibiting elastomeric properties. Newly synthesized copolyether-esters are presented and their solid-state properties, hydrolytic degradation profiles and biocompatibility are discussed and related with copolymer molecular structure.
C. Gualandi, M.L. Focarete, M. Soccio, N. Lotti, A. Munari, L. Visai (2011). New copolyether-esters from reactive blending for soft tissue engineering. S.N. : s.n.
New copolyether-esters from reactive blending for soft tissue engineering
GUALANDI, CHIARA;FOCARETE, MARIA LETIZIA;SOCCIO, MICHELINA;LOTTI, NADIA;MUNARI, ANDREA;
2011
Abstract
Materials with low elastic modulus (E) are expected to satisfy the required compliance of soft tissue engineering applications (E in the range 0.1-100 MPa, according to the specific tissue). Accordingly, the interest towards new elastomeric materials with controllable degradation profiles has increased significantly in the last decade3. In this work we propose reactive blending as a simple and versatile solvent-free synthetic approach to produce new biomaterials exhibiting elastomeric properties. Newly synthesized copolyether-esters are presented and their solid-state properties, hydrolytic degradation profiles and biocompatibility are discussed and related with copolymer molecular structure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
