The present invention relates to a portable device for the detection of analytes, in particular toxic substances, comprising at least a whole-cell biosensor with cells immobilized onto a transparent and inert matrix that allows the maintenance of cell vitality. The matrix comprises a mixture of collagen and/or its enzyme degradation derivatives, a proteoglycan and a mixture of vinyl polymer and an optionally modified polysiloxane, and an orthosilicate. The biosensor can be a genetically modified cell that expresses luciferase as reporter gene.
PORTABLE DEVICE BASED ON IMMOBILIZED CELLS FOR THE DETECTION OF ANALYTES / Michelini E; Roda A; Dolci L.S.; Cevenini L.; Mezzanotte L.. - (2010).
PORTABLE DEVICE BASED ON IMMOBILIZED CELLS FOR THE DETECTION OF ANALYTES
MICHELINI, ELISA;RODA, ALDO;DOLCI, LUISA STELLA;CEVENINI, LUCA;MEZZANOTTE, LAURA
2010
Abstract
The present invention relates to a portable device for the detection of analytes, in particular toxic substances, comprising at least a whole-cell biosensor with cells immobilized onto a transparent and inert matrix that allows the maintenance of cell vitality. The matrix comprises a mixture of collagen and/or its enzyme degradation derivatives, a proteoglycan and a mixture of vinyl polymer and an optionally modified polysiloxane, and an orthosilicate. The biosensor can be a genetically modified cell that expresses luciferase as reporter gene.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
