PRATI, LUCA
PRATI, LUCA
DIPARTIMENTO DI CHIMICA INDUSTRIALE "TOSO MONTANARI"
DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target
2024 Lucaroni, L.; Oehler, S.; Georgiev, T.; Muller, M.; Bocci, M.; De Luca, R.; Favalli, N.; Neri, D.; Cazzamalli, S.; Prati, L.
In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment
2024 Bocci, M.; Zana, A.; Principi, L.; Lucaroni, L.; Prati, L.; Gilardoni, E.; Neri, D.; Cazzamalli, S.; Galbiati, A.
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition
2023 Oehler, S.; Lucaroni, L.; Migliorini, F.; Elsayed, A.; Prati, L.; Puglioli, S.; Matasci, M.; Schira, K.; Scheuermann, J.; Yudin, D.; Jia, M.; Ban, N.; Bushnell, D.; Kornberg, R.; Cazzamalli, S.; Neri, D.; Favalli, N.; Bassi, G.
Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics
2023 Lucaroni, L.; Georgiev, T.; Prodi, E.; Puglioli, S.; Pellegrino, C.; Favalli, N.; Prati, L.; Manz, M. G.; Cazzamalli, S.; Neri, D.; Oehler, S.; Bassi, G.
Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries
2023 Torng, W.; Biancofiore, I.; Oehler, S.; Xu, J.; Xu, J.; Watson, I.; Masina, B.; Prati, L.; Favalli, N.; Bassi, G.; Neri, D.; Cazzamalli, S.; Feng, J. A.
Impact of library input on the hit discovery rate in DNA-encoded chemical library selections
2023 Puglioli, S.; Oehler, S.; Prati, L.; Scheuermann, J.; Bassi, G.; Cazzamalli, S.; Neri, D.; Favalli, N.
Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library
2023 Puglioli, S.; Schmidt, E.; Pellegrino, C.; Prati, L.; Oehler, S.; De Luca, R.; Galbiati, A.; Comacchio, C.; Nadal, L.; Scheuermann, J.; Manz, M. G.; Neri, D.; Cazzamalli, S.; Bassi, G.; Favalli, N.
Isolation of a Natural Killer Group 2D Small-Molecule Ligand from DNA-Encoded Chemical Libraries
2022 Dakhel, S.; Galbiati, A.; Migliorini, F.; Comacchio, C.; Oehler, S.; Prati, L.; Scheuermann, J.; Cazzamalli, S.; Neri, D.; Bassi, G.; Favalli, N.
Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries
2021 Gironda-Martinez, A.; Gorre, E. M. D.; Prati, L.; Gosalbes, J. -F.; Dakhel, S.; Cazzamalli, S.; Samain, F.; Donckele, E. J.; Neri, D.
Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands
2020 Catalano, M.; Oehler, S.; Prati, L.; Favalli, N.; Bassi, G.; Scheuermann, J.; Neri, D.
Critical Evaluation of Photo-cross-linking Parameters for the Implementation of Efficient DNA-Encoded Chemical Library Selections
2020 Sannino, A.; Gironda-Martinez, A.; Gorre, E. M. D.; Prati, L.; Piazzi, J.; Scheuermann, J.; Neri, D.; Donckele, E. J.; Samain, F.
On-DNA hit validation methodologies for ligands identified from DNA-encoded chemical libraries
2020 Prati, L.; Bigatti, M.; Donckele, E. J.; Neri, D.; Samain, F.
Conformational Analysis and Absolute Configuration of Axially Chiral 1-Aryl and 1,3-Bisaryl-xanthines
2017 Mancinelli, Michele; Perticarari, Sofia; Prati, Luca; Mazzanti, Andrea
Tetrasubstituted cyclopentadienones as suitable enantiopure ligands with axial chirality
2017 Prati, L.; Mancinelli, M.; Ciogli, A.; Mazzanti, A.
Computational and DNMR Analysis of the Conformational Isomers and Stereodynamics of Secondary 2,2′-Bisanilides
2016 Mazzanti, Andrea; Chiarucci, Michel; Prati, Luca; Bentley, Keith W.; Wolf, Christian
New azo-decorated: N -pyrrolidinylthiazoles: Synthesis, properties and an unexpected remote substituent effect transmission
2016 Boga, C; Cino, S; Micheletti, G; Padovan, D; Prati, L; Mazzanti, A; Zanna, N
Long-range bonding/nonbonding interactions: A donor-acceptor resonance studied by dynamic NMR
2015 Ruzziconi, R.; Lepri, S.; Buonerba, F.; Schlosser, M.; Mancinelli, M.; Ranieri, S.; Prati, L.; Mazzanti, A.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target | Lucaroni, L.; Oehler, S.; Georgiev, T.; Muller, M.; Bocci, M.; De Luca, R.; Favalli, N.; Neri, D....; Cazzamalli, S.; Prati, L. | 2024-01-01 | CHEMICAL SCIENCE | - | 1.01 Articolo in rivista | Prati_main.pdf; d3sc06668a1_SI.pdf |
| In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment | Bocci, M.; Zana, A.; Principi, L.; Lucaroni, L.; Prati, L.; Gilardoni, E.; Neri, D.; Cazzamalli, ...S.; Galbiati, A. | 2024-01-01 | JOURNAL OF CONTROLLED RELEASE | - | 1.01 Articolo in rivista | - |
| A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition | Oehler, S.; Lucaroni, L.; Migliorini, F.; Elsayed, A.; Prati, L.; Puglioli, S.; Matasci, M.; Schi...ra, K.; Scheuermann, J.; Yudin, D.; Jia, M.; Ban, N.; Bushnell, D.; Kornberg, R.; Cazzamalli, S.; Neri, D.; Favalli, N.; Bassi, G. | 2023-01-01 | NATURE CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics | Lucaroni, L.; Georgiev, T.; Prodi, E.; Puglioli, S.; Pellegrino, C.; Favalli, N.; Prati, L.; Manz..., M. G.; Cazzamalli, S.; Neri, D.; Oehler, S.; Bassi, G. | 2023-01-01 | EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING | - | 1.01 Articolo in rivista | - |
| Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries | Torng, W.; Biancofiore, I.; Oehler, S.; Xu, J.; Xu, J.; Watson, I.; Masina, B.; Prati, L.; Favall...i, N.; Bassi, G.; Neri, D.; Cazzamalli, S.; Feng, J. A. | 2023-01-01 | ACS OMEGA | - | 1.01 Articolo in rivista | - |
| Impact of library input on the hit discovery rate in DNA-encoded chemical library selections | Puglioli, S.; Oehler, S.; Prati, L.; Scheuermann, J.; Bassi, G.; Cazzamalli, S.; Neri, D.; Favall...i, N. | 2023-01-01 | CHEMICAL SCIENCE | - | 1.01 Articolo in rivista | - |
| Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library | Puglioli, S.; Schmidt, E.; Pellegrino, C.; Prati, L.; Oehler, S.; De Luca, R.; Galbiati, A.; Coma...cchio, C.; Nadal, L.; Scheuermann, J.; Manz, M. G.; Neri, D.; Cazzamalli, S.; Bassi, G.; Favalli, N. | 2023-01-01 | CHEM | - | 1.01 Articolo in rivista | - |
| Isolation of a Natural Killer Group 2D Small-Molecule Ligand from DNA-Encoded Chemical Libraries | Dakhel, S.; Galbiati, A.; Migliorini, F.; Comacchio, C.; Oehler, S.; Prati, L.; Scheuermann, J.; ...Cazzamalli, S.; Neri, D.; Bassi, G.; Favalli, N. | 2022-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries | Gironda-Martinez, A.; Gorre, E. M. D.; Prati, L.; Gosalbes, J. -F.; Dakhel, S.; Cazzamalli, S.; S...amain, F.; Donckele, E. J.; Neri, D. | 2021-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands | Catalano, M.; Oehler, S.; Prati, L.; Favalli, N.; Bassi, G.; Scheuermann, J.; Neri, D. | 2020-01-01 | ANALYTICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Critical Evaluation of Photo-cross-linking Parameters for the Implementation of Efficient DNA-Encoded Chemical Library Selections | Sannino, A.; Gironda-Martinez, A.; Gorre, E. M. D.; Prati, L.; Piazzi, J.; Scheuermann, J.; Neri,... D.; Donckele, E. J.; Samain, F. | 2020-01-01 | ACS COMBINATORIAL SCIENCE | - | 1.01 Articolo in rivista | - |
| On-DNA hit validation methodologies for ligands identified from DNA-encoded chemical libraries | Prati, L.; Bigatti, M.; Donckele, E. J.; Neri, D.; Samain, F. | 2020-01-01 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - | 1.01 Articolo in rivista | - |
| Conformational Analysis and Absolute Configuration of Axially Chiral 1-Aryl and 1,3-Bisaryl-xanthines | Mancinelli, Michele; Perticarari, Sofia; Prati, Luca; Mazzanti, Andrea | 2017-01-01 | JOURNAL OF ORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Tetrasubstituted cyclopentadienones as suitable enantiopure ligands with axial chirality | Prati, L.; Mancinelli, M.; Ciogli, A.; Mazzanti, A. | 2017-01-01 | ORGANIC & BIOMOLECULAR CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Computational and DNMR Analysis of the Conformational Isomers and Stereodynamics of Secondary 2,2′-Bisanilides | Mazzanti, Andrea; Chiarucci, Michel; Prati, Luca; Bentley, Keith W.; Wolf, Christian | 2016-01-01 | JOURNAL OF ORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| New azo-decorated: N -pyrrolidinylthiazoles: Synthesis, properties and an unexpected remote substituent effect transmission | Boga, C; Cino, S; Micheletti, G; Padovan, D; Prati, L; Mazzanti, A; Zanna, N | 2016-01-01 | ORGANIC & BIOMOLECULAR CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Long-range bonding/nonbonding interactions: A donor-acceptor resonance studied by dynamic NMR | Ruzziconi, R.; Lepri, S.; Buonerba, F.; Schlosser, M.; Mancinelli, M.; Ranieri, S.; Prati, L.; Ma...zzanti, A. | 2015-01-01 | ORGANIC LETTERS | - | 1.01 Articolo in rivista | - |