MINGUZZI, MANUELA
MINGUZZI, MANUELA
ARIC - AREA RICERCA
Personale tecnico amm.vo
CDKN1C/P57 Is Regulated by the Notch Target Gene Hes1 and Induces Senescence in Human Hepatocellular Carcinoma.
2012 Giovannini C.; Gramantieri L.; Minguzzi M.; Fornari F.; Chieco P.; Grazi G.L.; Bolondi L.
Cell death in human articular chondrocyte: a morpho-functional study in micromass model
2014 Michela Battistelli; Sara Salucci; Eleonora Olivotto; Annalisa Facchini; Manuela Minguzzi; Serena Guidotti; Stefania Pagani; Flavio Flamigni; Rosa Maria Borzì; Andrea Facchini; Elisabetta Falcieri
Chondroprotective and anti-oxidant activity of spermidine in human chondrocytes
2018 Silvestri, Y.; D'adamo, S.; Cetrullo, S.; Minguzzi, M.; Guidotti, S.; Filardo, G.; Mariani, E.; Borzì, R.; Flamigni, F.
Design, Synthesis and Biological Evaluation of Pyrazole derivatives as Potential multikinase Inhibitors in Hepatocarcinoma.
2012 F. Fornari; M. Minguzzi; E. Strocchi; E. Locatelli; L. Gramantieri; M. Milazzo; V. Rebuttini; S. Breviglieri; C. M. Camaggi; L. Bolondi; M. Comes Franchini
Effects of Notch1 knockdown on the proliferation and the differentiation of human articular chondrocytes
2018 Manuela Minguzzi, V. Panichi, L. Cattini, G. Filardo, E. Mariani, R. M. Borzì
Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis
2018 Minguzzi, Manuela; Cetrullo, Silvia; D’Adamo, Stefania; Silvestri, Ylenia; Flamigni, Flavio; Borzì, Rosa Maria
Emerging roles of spermidine in human chondrocyte protection: oxidative stress resistance and induction of autophagy
2017 Silvestri, Y; D'Adamo, S; Cetrullo, S; Minguzzi, M; Guidotti, S; Filardo, G; Mariani, E; Borzi, Rm; Flamigni, F.
Enhanced Osteoblastogenesis of Adipose-Derived Stem Cells on Spermine Delivery via β-Catenin Activation
2013 Serena Guidotti;Annalisa Facchini;Daniela Platano;Eleonora Olivotto;Manuela Minguzzi;Giovanni Trisolino;Giuseppe Filardo;Silvia Cetrullo;Benedetta Tantini;Ermanno Martucci;Andrea Facchini;Flavio Flamigni;Rosa Maria Borzì
F.N.27 NOTCH SIGNALLING CONTROLS PROLIFERATION AND SENESCENCE OF HUMAN HEPATOCELLULAR CARCINOMA
2010 Minguzzi, M.; Giovannini, C.; Gramantieri, L.; Fornari, F.; Chieco, P.; Piscaglia, F.; Bolondi, L.
Glycogen synthase kinase -3β inhibition leads to mitochondrial dysfunction, extracellular matrix remodelling and terminal differentiation of human chondrocytes.
2017 Minguzzi M., Guidotti S, Platano D, Santi S , Filardo G., Mariani E., Borzì R.M.
Glycogen Synthase Kinase-3β Inhibition Links Mitochondrial Dysfunction, Extracellular Matrix Remodelling and Terminal Differentiation in Chondrocytes
2017 Guidotti, S.; Minguzzi, M.; Platano, D.; Santi, S.; Trisolino, G.; Filardo, G.; Mariani, E.; Borzì, R. M.
GSK3 beta: a key regulator of oxidative stress in 3D-cultures of osteoarthritic chondrocytes
2015 Guidotti, S; Minguzzi, M; Platano, D; Santi, S; Mariani, E; Trisolino, G; Filardo, G; Borzi, Rm
GSK3β inhibiton in osteoarthritic human primary chondrocytes determines oxidative stress and DNA damage response leading to senescence or apoptosis in different stimulatory contexts.
2014 Manuela Minguzzi, Serena Guidotti, D. Platano, E . Olivotto, A. Facchini L. Cattini, F. Flamigni, G. Trisolino, A. Facchini, R.M. Borzì
Hydroxytyrosol attenuates the hypomethylation of miR-9 promoters induced by oxidative stress
2018 Stefania D’Adamo, S Cetrullo, Y Silvestri, M Minguzzi, RM Borzì, F Flamigni
Hydroxytyrosol Prevents Increase of Osteoarthritis Markers in Human Chondrocytes Treated with Hydrogen Peroxide or Growth-Related Oncogene α
2014 Annalisa Facchini; Silvia Cetrullo; Stefania D'Adamo; Serena Guidotti; Manuela Minguzzi; Andrea Facchini; Rosa Maria Borzi; Flavio Flamigni
Lithium chloride dependent glycogen synthase kinase 3 inactivation links oxidative DNA damage, hypertrophy and senescence in human articular chondrocytes and reproduces chondrocyte phenotype of obese osteoarthritis patients
2015 Guidotti, Serena; Minguzzi, Manuela; Platano, Daniela; Cattini, Luca; Trisolino, Giovanni; Mariani, Erminia; Borzì, Rosa Maria
MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis
2017 D'Adamo, Stefania; Cetrullo, Silvia; Minguzzi, Manuela; Silvestri, Ylenia; Borzì, Rosa Maria; Flamigni, Flavio
Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma
2016 Giovannini, Catia; Minguzzi, Manuela; Genovese, Filippo; Baglioni, Michele; Gualandi, Alessandra; Ravaioli, Matteo; Milazzo, Maddalena; Tavolari, Simona; Bolondi, Luigi; Gramantieri, Laura
Pleiotropic roles of notch1 signaling in the loss of maturational arrest of human osteoarthritic chondrocytes
2021 Minguzzi M.; Panichi V.; D'adamo S.; Cetrullo S.; Cattini L.; Flamigni F.; Mariani E.; Borzi R.M.
Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering
2014 Rosa Maria Borzì;Serena Guidotti;Manuela Minguzzi;Annalisa Facchini;Daniela Platano;Giovanni Trisolino;Giuseppe Filardo;Silvia Cetrullo;Stefania D’Adamo;Claudio Stefanelli;Andrea Facchini;Flavio Flamigni
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| CDKN1C/P57 Is Regulated by the Notch Target Gene Hes1 and Induces Senescence in Human Hepatocellular Carcinoma. | Giovannini C.; Gramantieri L.; Minguzzi M.; Fornari F.; Chieco P.; Grazi G.L.; Bolondi L. | 2012-01-01 | THE AMERICAN JOURNAL OF PATHOLOGY | - | 1.01 Articolo in rivista | - |
| Cell death in human articular chondrocyte: a morpho-functional study in micromass model | Michela Battistelli; Sara Salucci; Eleonora Olivotto; Annalisa Facchini; Manuela Minguzzi; Serena... Guidotti; Stefania Pagani; Flavio Flamigni; Rosa Maria Borzì; Andrea Facchini; Elisabetta Falcieri | 2014-01-01 | APOPTOSIS | - | 1.01 Articolo in rivista | - |
| Chondroprotective and anti-oxidant activity of spermidine in human chondrocytes | Silvestri, Y.; D'adamo, S.; Cetrullo, S.; Minguzzi, M.; Guidotti, S.; Filardo, G.; Mariani, E.; B...orzì, R.; Flamigni, F. | 2018-01-01 | OSTEOARTHRITIS AND CARTILAGE | ELSEVIER SCI LTD | 4.02 Riassunto (Abstract) | - |
| Design, Synthesis and Biological Evaluation of Pyrazole derivatives as Potential multikinase Inhibitors in Hepatocarcinoma. | F. Fornari; M. Minguzzi; E. Strocchi; E. Locatelli; L. Gramantieri; M. Milazzo; V. Rebuttini; S. ...Breviglieri; C. M. Camaggi; L. Bolondi; M. Comes Franchini | 2012-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Effects of Notch1 knockdown on the proliferation and the differentiation of human articular chondrocytes | Manuela Minguzzi, V. Panichi, L. Cattini, G. Filardo, E. Mariani, R. M. Borzì | 2018-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Emerging Players at the Intersection of Chondrocyte Loss of Maturational Arrest, Oxidative Stress, Senescence and Low-Grade Inflammation in Osteoarthritis | Minguzzi, Manuela; Cetrullo, Silvia; D’Adamo, Stefania; Silvestri, Ylenia; Flamigni, Flavio; Borz...ì, Rosa Maria | 2018-01-01 | OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | - | 1.01 Articolo in rivista | 3075293.pdf |
| Emerging roles of spermidine in human chondrocyte protection: oxidative stress resistance and induction of autophagy | Silvestri, Y; D'Adamo, S; Cetrullo, S; Minguzzi, M; Guidotti, S; Filardo, G; Mariani, E; Borzi, R...m; Flamigni, F. | 2017-01-01 | THE FEBS JOURNAL | WILEY | 4.02 Riassunto (Abstract) | - |
| Enhanced Osteoblastogenesis of Adipose-Derived Stem Cells on Spermine Delivery via β-Catenin Activation | Serena Guidotti;Annalisa Facchini;Daniela Platano;Eleonora Olivotto;Manuela Minguzzi;Giovanni Tri...solino;Giuseppe Filardo;Silvia Cetrullo;Benedetta Tantini;Ermanno Martucci;Andrea Facchini;Flavio Flamigni;Rosa Maria Borzì | 2013-01-01 | STEM CELLS AND DEVELOPMENT | - | 1.01 Articolo in rivista | - |
| F.N.27 NOTCH SIGNALLING CONTROLS PROLIFERATION AND SENESCENCE OF HUMAN HEPATOCELLULAR CARCINOMA | Minguzzi, M.; Giovannini, C.; Gramantieri, L.; Fornari, F.; Chieco, P.; Piscaglia, F.; Bolondi, L. | 2010-01-01 | DIGESTIVE AND LIVER DISEASE | - | 4.02 Riassunto (Abstract) | - |
| Glycogen synthase kinase -3β inhibition leads to mitochondrial dysfunction, extracellular matrix remodelling and terminal differentiation of human chondrocytes. | Minguzzi M., Guidotti S, Platano D, Santi S , Filardo G., Mariani E., Borzì R.M. | 2017-01-01 | - | CSSI, Cell Stress Society International | 4.01 Contributo in Atti di convegno | - |
| Glycogen Synthase Kinase-3β Inhibition Links Mitochondrial Dysfunction, Extracellular Matrix Remodelling and Terminal Differentiation in Chondrocytes | Guidotti, S.; Minguzzi, M.; Platano, D.; Santi, S.; Trisolino, G.; Filardo, G.; Mariani, E.; Borz...ì, R. M. | 2017-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | Sci Rep 2017 41598_2017_Article_12129 Guidotti Glycogen Synthase.pdf |
| GSK3 beta: a key regulator of oxidative stress in 3D-cultures of osteoarthritic chondrocytes | Guidotti, S; Minguzzi, M; Platano, D; Santi, S; Mariani, E; Trisolino, G; Filardo, G; Borzi, Rm | 2015-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| GSK3β inhibiton in osteoarthritic human primary chondrocytes determines oxidative stress and DNA damage response leading to senescence or apoptosis in different stimulatory contexts. | Manuela Minguzzi, Serena Guidotti, D. Platano, E . Olivotto, A. Facchini L. Cattini, F. Flamigni..., G. Trisolino, A. Facchini, R.M. Borzì | 2014-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Hydroxytyrosol attenuates the hypomethylation of miR-9 promoters induced by oxidative stress | Stefania D’Adamo, S Cetrullo, Y Silvestri, M Minguzzi, RM Borzì, F Flamigni | 2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Hydroxytyrosol Prevents Increase of Osteoarthritis Markers in Human Chondrocytes Treated with Hydrogen Peroxide or Growth-Related Oncogene α | Annalisa Facchini; Silvia Cetrullo; Stefania D'Adamo; Serena Guidotti; Manuela Minguzzi; Andrea F...acchini; Rosa Maria Borzi; Flavio Flamigni | 2014-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | journal.pone.0109724.pdf |
| Lithium chloride dependent glycogen synthase kinase 3 inactivation links oxidative DNA damage, hypertrophy and senescence in human articular chondrocytes and reproduces chondrocyte phenotype of obese osteoarthritis patients | Guidotti, Serena; Minguzzi, Manuela; Platano, Daniela; Cattini, Luca; Trisolino, Giovanni; Marian...i, Erminia; Borzì, Rosa Maria | 2015-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | PlosOne 2015 Borzi.pdf |
| MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis | D'Adamo, Stefania; Cetrullo, Silvia; Minguzzi, Manuela; Silvestri, Ylenia; Borzì, Rosa Maria; Fla...migni, Flavio | 2017-01-01 | OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | - | 1.01 Articolo in rivista | OMCL-3720128.pdf |
| Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma | Giovannini, Catia; Minguzzi, Manuela; Genovese, Filippo; Baglioni, Michele; Gualandi, Alessandra;... Ravaioli, Matteo; Milazzo, Maddalena; Tavolari, Simona; Bolondi, Luigi; Gramantieri, Laura | 2016-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Pleiotropic roles of notch1 signaling in the loss of maturational arrest of human osteoarthritic chondrocytes | Minguzzi M.; Panichi V.; D'adamo S.; Cetrullo S.; Cattini L.; Flamigni F.; Mariani E.; Borzi R.M. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-12012.pdf; ijms-1320137-supplementary.pdf |
| Polyamine delivery as a tool to modulate stem cell differentiation in skeletal tissue engineering | Rosa Maria Borzì;Serena Guidotti;Manuela Minguzzi;Annalisa Facchini;Daniela Platano;Giovanni Tris...olino;Giuseppe Filardo;Silvia Cetrullo;Stefania D’Adamo;Claudio Stefanelli;Andrea Facchini;Flavio Flamigni | 2014-01-01 | AMINO ACIDS | - | 1.01 Articolo in rivista | - |