RUZZI, FRANCESCA
RUZZI, FRANCESCA
DIMEC - DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Personale tecnico amm.vo
Cancer vaccines: Target antigens, vaccine platforms and preclinical models
2025 Ruzzi, Francesca; Riccardo, Federica; Conti, Laura; Tarone, Lidia; Semprini, Maria Sofia; Bolli, Elisabetta; Barutello, Giuseppina; Quaglino, Elena; Lollini, Pier-Luigi; Cavallo, Federica
Chondrosarcoma: New Molecular Insights, Challenges in Near-Patient Preclinical Modeling, and Therapeutic Approaches
2025 Landuzzi, L; Ruzzi, F; Lollini, Pl; Scotlandi, K
PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD)
2025 Angelicola, Stefania; Giunchi, Francesca; Ruzzi, Francesca; Frascino, Mariateresa; Pitzalis, Mary; Scalambra, Laura; Semprini, Maria Sofia; Pittino, Olga Maria; Cappello, Chiara; Siracusa, Irene; Chillico, Ilaria Candida; Di Noia, Martina; Turato, Cristian; De Siervi, Silvia; Lescai, Francesco; Ciavattini, Teresa; Lopatriello, Giulia; Bertoli, Luca; De Jonge, Hugo; Iamele, Luisa; Altimari, Annalisa; Gruppioni, Elisa; Ardizzoni, Andrea; Rossato, Marzia; Gelsomino, Francesco; Lollini, Pier-Luigi; Palladini, Arianna
Targeting PCSK9, through an innovative cVLP-based vaccine, enhanced the therapeutic activity of a cVLP-HER2 vaccine in a preclinical model of HER2-positive mammary carcinoma
2025 Scalambra, Laura; Ruzzi, Francesca; Pittino, Olga Maria; Semprini, Maria Sofia; Cappello, Chiara; Angelicola, Stefania; Palladini, Arianna; Nanni, Patrizia; Goksøyr, Louise; Fougeroux, Cyrielle; Penichet, Manuel L; Sander, Adam Frederik; Lollini, Pier-Luigi
CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1-targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape
2024 Pasello M.; Laginestra M.A.; Manara M.C.; Landuzzi L.; Ruzzi F.; Maioli M.; Pellegrini E.; De Feo A.; Lollini P.-L.; Scotlandi K.
Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations
2024 Di Federico, Alessandro; Angelicola, Stefania; Frascino, Mariateresa; Siracusa, Irene; Bisanti, Beatrice; Ruzzi, Francesca; Semprini, Maria Sofia; De Jonge, Hugo; De Giglio, Andrea; Sperandi, Francesca; Brocchi, Stefano; Melotti, Barbara; Giunchi, Francesca; Gruppioni, Elisa; Altimari, Annalisa; Lollini, Pier-Luigi; Ardizzoni, Andrea; Palladini, Arianna; Gelsomino, Francesco
Functional evaluation of circulating anti-cancer antibodies with a 3D tumor cell growth inhibition assay
2024 Ruzzi F.; Semprini M.S.; Scalambra L.; Angelicola S.; Cappello C.; Pittino O.M.; Nanni P.; Palladini A.; Lollini P.L.
IL-1 Family Members in Bone Sarcomas
2024 Lorena Landuzzi, Francesca Ruzzi, Evelin Pellegrini, Pier-Luigi Lollini, Katia Scotlandi, Maria Cristina Manara
Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes?
2024 Ruzzi, Francesca; Cappello, Chiara; Semprini, Maria Sofia; Scalambra, Laura; Angelicola, Stefania; Pittino, Olga Maria; Landuzzi, Lorena; Palladini, Arianna; Nanni, Patrizia; Lollini, Pier-Luigi
Preclinical activity of ES2B-C001, a human candidate HER-2 virus-like particle (VLP) vaccine, against mammary carcinoma onset and metastasis
2023 Ruzzi, F; Palladini, A; Clemmensen, S; Strobaek, A; Buijs, N; Domeyer, T; Dorosz, J; Soroka, V; Grzadziela, D; Rasmussen, CJ; Nielsen, IB; Soegaard, M; Semprini, MS; Scalambra, L; Angelicola, S; Landuzzi, L; Lollini, PL; Thorn, M
Synovial Sarcoma Preclinical Modeling: Integrating Transgenic Mouse Models and Patient-Derived Models for Translational Research
2023 Lorena Landuzzi, Francesca Ruzzi, Pier-Luigi Lollini, Katia Scotlandi
Virus-like Particle (VLP) Vaccines for Cancer Immunotherapy
2023 Ruzzi F.; Semprini M.S.; Scalambra L.; Palladini A.; Angelicola S.; Cappello C.; Pittino O.M.; Nanni P.; Lollini P.-L.
ADK-VR2, a cell line derived from a treatment-naïve patient with SDC4-ROS1 fusion-positive primarily crizotinib-resistant NSCLC: a novel preclinical model for new drug development of ROS1- rearranged NSCLC
2022 Ruzzi, Francesca; Angelicola, Stefania; Landuzzi, Lorena; Nironi, Elena; Semprini, Maria Sofia; Scalambra, Laura; Altimari, Annalisa; Gruppioni, Elisa; Fiorentino, Michelangelo; Giunchi, Francesca; Ferracin, Manuela; Astolfi, Annalisa; Indio, Valentina; Ardizzoni, Andrea; Gelsomino, Francesco; Nanni, Patrizia; Lollini, Pier-Luigi; Palladini, Arianna
CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality
2022 Sorrentino, Carlo; D'Antonio, Luigi; Ciummo, Stefania Livia; Fieni, Cristiano; Landuzzi, Lorena; Ruzzi, Francesca; Vespa, Simone; Lanuti, Paola; Lotti, Lavinia Vittoria; Lollini, Pier Luigi; Di Carlo, Emma
Integrated molecular characterization of patient-derived models reveals therapeutic strategies for treating CIC-DUX4 sarcoma
2022 Carrabotta, Marianna; Laginestra, Maria Antonella; Durante, Giorgio; Mancarella, Caterina; Landuzzi, Lorena; Parra, Alessandro; Ruzzi, Francesca; Toracchio, Lisa; De Feo, Alessandra; Giusti, Veronica; Pasello, Michela; Righi, Alberto; Lollini, Pier-Luigi; Palmerini, Emanuela; Donati, Davide Maria; Manara, Maria Cristina; Scotlandi, Katia
Prevention and Therapy of Metastatic HER-2+ Mammary Carcinoma with a Human Candidate HER-2 Virus-like Particle Vaccine
2022 Ruzzi, Francesca; Palladini, Arianna; Clemmensen, Stine; Strøbæk, Anette; Buijs, Nicolaas; Domeyer, Tanja; Dorosz, Jerzy; Soroka, Vladislav; Grzadziela, Dagmara; Rasmussen, Christina Jo; Nielsen, Ida Busch; Soegaard, Max; Semprini, Maria Sofia; Scalambra, Laura; Angelicola, Stefania; Landuzzi, Lorena; Lollini, Pier-Luigi; Thorn, Mette
Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft
2021 Landuzzi, Lorena; Palladini, Arianna; Ceccarelli, Claudio; Asioli, Sofia; Nicoletti, Giordano; Giusti, Veronica; Ruzzi, Francesca; Ianzano, Marianna L; Scalambra, Laura; Laranga, Roberta; Balboni, Tania; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele A; De Giovanni, Carla; Dall'Ora, Massimiliano; Di Oto, Enrico; Santini, Donatella; Foschini, Maria Pia; Cucchi, Maria Cristina; Zanotti, Simone; Taffurelli, Mario; Nanni, Patrizia; Lollini, Pier-Luigi
Evolution of HER2-positive mammary carcinoma: HER2 loss reveals claudin-low traits in cancer progression
2021 Giusti, Veronica; Ruzzi, Francesca; Landuzzi, Lorena; Ianzano, Marianna L; Laranga, Roberta; Nironi, Elena; Scalambra, Laura; Nicoletti, Giordano; De Giovanni, Carla; Olivero, Martina; Arigoni, Maddalena; Calogero, Raffaele; Nanni, Patrizia; Palladini, Arianna; Lollini, Pier-Luigi
IFN-γ and CD38 in Hyperprogressive Cancer Development
2021 Angelicola, Stefania; Ruzzi, Francesca; Landuzzi, Lorena; Scalambra, Laura; Gelsomino, Francesco; Ardizzoni, Andrea; Nanni, Patrizia; Lollini, Pier-Luigi; Palladini, Arianna
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations
2019 Nanni, Patrizia; Landuzzi, Lorena; Manara, Maria Cristina; Righi, Alberto; Nicoletti, Giordano; Cristalli, Camilla; Pasello, Michela; Parra, Alessandro; Carrabotta, Marianna; Ferracin, Manuela; Palladini, Arianna; Ianzano, Marianna L; Giusti, Veronica; Ruzzi, Francesca; Magnani, Mauro; Donati, Davide Maria; Picci, Piero; Lollini, Pier-Luigi; Scotlandi, Katia
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Cancer vaccines: Target antigens, vaccine platforms and preclinical models | Ruzzi, Francesca; Riccardo, Federica; Conti, Laura; Tarone, Lidia; Semprini, Maria Sofia; Bolli, ...Elisabetta; Barutello, Giuseppina; Quaglino, Elena; Lollini, Pier-Luigi; Cavallo, Federica | 2025-01-01 | MOLECULAR ASPECTS OF MEDICINE | - | 1.01 Articolo in rivista | Vax Review MAM.pdf |
| Chondrosarcoma: New Molecular Insights, Challenges in Near-Patient Preclinical Modeling, and Therapeutic Approaches | Landuzzi, L; Ruzzi, F; Lollini, Pl; Scotlandi, K | 2025-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | Chondrosarcoma review ijms-26-01542.pdf |
| PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD) | Angelicola, Stefania; Giunchi, Francesca; Ruzzi, Francesca; Frascino, Mariateresa; Pitzalis, Mary...; Scalambra, Laura; Semprini, Maria Sofia; Pittino, Olga Maria; Cappello, Chiara; Siracusa, Irene; Chillico, Ilaria Candida; Di Noia, Martina; Turato, Cristian; De Siervi, Silvia; Lescai, Francesco; Ciavattini, Teresa; Lopatriello, Giulia; Bertoli, Luca; De Jonge, Hugo; Iamele, Luisa; Altimari, Annalisa; Gruppioni, Elisa; Ardizzoni, Andrea; Rossato, Marzia; Gelsomino, Francesco; Lollini, Pier-Luigi; Palladini, Arianna | 2025-01-01 | JOURNAL OF TRANSLATIONAL MEDICINE | - | 1.01 Articolo in rivista | Hyperprog NSCLC JTranslMed.pdf; 12967_2024_6023_MOESM3_ESM.zip |
| Targeting PCSK9, through an innovative cVLP-based vaccine, enhanced the therapeutic activity of a cVLP-HER2 vaccine in a preclinical model of HER2-positive mammary carcinoma | Scalambra, Laura; Ruzzi, Francesca; Pittino, Olga Maria; Semprini, Maria Sofia; Cappello, Chiara;... Angelicola, Stefania; Palladini, Arianna; Nanni, Patrizia; Goksøyr, Louise; Fougeroux, Cyrielle; Penichet, Manuel L; Sander, Adam Frederik; Lollini, Pier-Luigi | 2025-01-01 | JOURNAL OF TRANSLATIONAL MEDICINE | - | 1.01 Articolo in rivista | PCSK9 JTranslMed.pdf; 12967_2025_6126_MOESM1_ESM.docx |
| CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1-targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape | Pasello M.; Laginestra M.A.; Manara M.C.; Landuzzi L.; Ruzzi F.; Maioli M.; Pellegrini E.; De Feo... A.; Lollini P.-L.; Scotlandi K. | 2024-01-01 | JOURNAL OF CELL COMMUNICATION AND SIGNALING | - | 1.01 Articolo in rivista | Journal of Cell Communication and Signaling - 2024 - Pasello - CD99 contributes to the EWS FLI1 transcriptome by.pdf |
| Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations | Di Federico, Alessandro; Angelicola, Stefania; Frascino, Mariateresa; Siracusa, Irene; Bisanti, B...eatrice; Ruzzi, Francesca; Semprini, Maria Sofia; De Jonge, Hugo; De Giglio, Andrea; Sperandi, Francesca; Brocchi, Stefano; Melotti, Barbara; Giunchi, Francesca; Gruppioni, Elisa; Altimari, Annalisa; Lollini, Pier-Luigi; Ardizzoni, Andrea; Palladini, Arianna; Gelsomino, Francesco | 2024-01-01 | JCO PRECISION ONCOLOGY | - | 1.01 Articolo in rivista | di-federico-et-al-2024-clinical-and-preclinical-activity-of-egfr-tyrosine-kinase-inhibitors-in-non-small-cell-lung.pdf; ds_po.24.00240.xlsx |
| Functional evaluation of circulating anti-cancer antibodies with a 3D tumor cell growth inhibition assay | Ruzzi F.; Semprini M.S.; Scalambra L.; Angelicola S.; Cappello C.; Pittino O.M.; Nanni P.; Pallad...ini A.; Lollini P.L. | 2024-01-01 | METHODS IN CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| IL-1 Family Members in Bone Sarcomas | Lorena Landuzzi, Francesca Ruzzi, Evelin Pellegrini, Pier-Luigi Lollini, Katia Scotlandi, Maria C...ristina Manara | 2024-01-01 | CELLS | - | 1.01 Articolo in rivista | IL-1 review Cells 2024.pdf |
| Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes? | Ruzzi, Francesca; Cappello, Chiara; Semprini, Maria Sofia; Scalambra, Laura; Angelicola, Stefania...; Pittino, Olga Maria; Landuzzi, Lorena; Palladini, Arianna; Nanni, Patrizia; Lollini, Pier-Luigi | 2024-01-01 | CELL COMMUNICATION AND SIGNALING | - | 1.01 Articolo in rivista | Lipid rafts review.pdf |
| Preclinical activity of ES2B-C001, a human candidate HER-2 virus-like particle (VLP) vaccine, against mammary carcinoma onset and metastasis | Ruzzi, F; Palladini, A; Clemmensen, S; Strobaek, A; Buijs, N; Domeyer, T; Dorosz, J; Soroka, V; G...rzadziela, D; Rasmussen, CJ; Nielsen, IB; Soegaard, M; Semprini, MS; Scalambra, L; Angelicola, S; Landuzzi, L; Lollini, PL; Thorn, M | 2023-01-01 | CANCER RESEARCH | - | 1.06 Abstract in rivista | - |
| Synovial Sarcoma Preclinical Modeling: Integrating Transgenic Mouse Models and Patient-Derived Models for Translational Research | Lorena Landuzzi, Francesca Ruzzi, Pier-Luigi Lollini, Katia Scotlandi | 2023-01-01 | CANCERS | - | 1.01 Articolo in rivista | Synovial cancers-15-00588.pdf |
| Virus-like Particle (VLP) Vaccines for Cancer Immunotherapy | Ruzzi F.; Semprini M.S.; Scalambra L.; Palladini A.; Angelicola S.; Cappello C.; Pittino O.M.; Na...nni P.; Lollini P.-L. | 2023-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | VLP Review ijms-24-12963-v2.pdf |
| ADK-VR2, a cell line derived from a treatment-naïve patient with SDC4-ROS1 fusion-positive primarily crizotinib-resistant NSCLC: a novel preclinical model for new drug development of ROS1- rearranged NSCLC | Ruzzi, Francesca; Angelicola, Stefania; Landuzzi, Lorena; Nironi, Elena; Semprini, Maria Sofia; S...calambra, Laura; Altimari, Annalisa; Gruppioni, Elisa; Fiorentino, Michelangelo; Giunchi, Francesca; Ferracin, Manuela; Astolfi, Annalisa; Indio, Valentina; Ardizzoni, Andrea; Gelsomino, Francesco; Nanni, Patrizia; Lollini, Pier-Luigi; Palladini, Arianna | 2022-01-01 | TRANSLATIONAL LUNG CANCER RESEARCH | - | 1.01 Articolo in rivista | ADK-VR2 TLCR.pdf; tlcr-11-11-2216-coif.zip |
| CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality | Sorrentino, Carlo; D'Antonio, Luigi; Ciummo, Stefania Livia; Fieni, Cristiano; Landuzzi, Lorena; ...Ruzzi, Francesca; Vespa, Simone; Lanuti, Paola; Lotti, Lavinia Vittoria; Lollini, Pier Luigi; Di Carlo, Emma | 2022-01-01 | JOURNAL OF HEMATOLOGY & ONCOLOGY | - | 1.01 Articolo in rivista | IL-30 Di Carlo J Hematol Oncol_compressed.pdf; 13045_2022_1357_MOESM1_ESM.docx; 13045_2022_1357_MOESM2_ESM.docx |
| Integrated molecular characterization of patient-derived models reveals therapeutic strategies for treating CIC-DUX4 sarcoma | Carrabotta, Marianna; Laginestra, Maria Antonella; Durante, Giorgio; Mancarella, Caterina; Landuz...zi, Lorena; Parra, Alessandro; Ruzzi, Francesca; Toracchio, Lisa; De Feo, Alessandra; Giusti, Veronica; Pasello, Michela; Righi, Alberto; Lollini, Pier-Luigi; Palmerini, Emanuela; Donati, Davide Maria; Manara, Maria Cristina; Scotlandi, Katia | 2022-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | CIC-DUX4 Cancer Res 2022.pdf; can-21-1222_supplementary_data_supp1-9.pdf; can-21-1222_supplementary_methods_and_figures_supp1-13.pdf |
| Prevention and Therapy of Metastatic HER-2+ Mammary Carcinoma with a Human Candidate HER-2 Virus-like Particle Vaccine | Ruzzi, Francesca; Palladini, Arianna; Clemmensen, Stine; Strøbæk, Anette; Buijs, Nicolaas; Domeye...r, Tanja; Dorosz, Jerzy; Soroka, Vladislav; Grzadziela, Dagmara; Rasmussen, Christina Jo; Nielsen, Ida Busch; Soegaard, Max; Semprini, Maria Sofia; Scalambra, Laura; Angelicola, Stefania; Landuzzi, Lorena; Lollini, Pier-Luigi; Thorn, Mette | 2022-01-01 | BIOMEDICINES | - | 1.01 Articolo in rivista | biomedicines-10-02654-v2.pdf; biomedicines-10-02654-s001.zip |
| Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft | Landuzzi, Lorena; Palladini, Arianna; Ceccarelli, Claudio; Asioli, Sofia; Nicoletti, Giordano; Gi...usti, Veronica; Ruzzi, Francesca; Ianzano, Marianna L; Scalambra, Laura; Laranga, Roberta; Balboni, Tania; Arigoni, Maddalena; Olivero, Martina; Calogero, Raffaele A; De Giovanni, Carla; Dall'Ora, Massimiliano; Di Oto, Enrico; Santini, Donatella; Foschini, Maria Pia; Cucchi, Maria Cristina; Zanotti, Simone; Taffurelli, Mario; Nanni, Patrizia; Lollini, Pier-Luigi | 2021-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | PDX Breast Sci Rep small.pdf |
| Evolution of HER2-positive mammary carcinoma: HER2 loss reveals claudin-low traits in cancer progression | Giusti, Veronica; Ruzzi, Francesca; Landuzzi, Lorena; Ianzano, Marianna L; Laranga, Roberta; Niro...ni, Elena; Scalambra, Laura; Nicoletti, Giordano; De Giovanni, Carla; Olivero, Martina; Arigoni, Maddalena; Calogero, Raffaele; Nanni, Patrizia; Palladini, Arianna; Lollini, Pier-Luigi | 2021-01-01 | ONCOGENESIS | - | 1.01 Articolo in rivista | HER-2 loss Oncogenesis.pdf; 41389_2021_360_MOESM1_ESM.pdf |
| IFN-γ and CD38 in Hyperprogressive Cancer Development | Angelicola, Stefania; Ruzzi, Francesca; Landuzzi, Lorena; Scalambra, Laura; Gelsomino, Francesco;... Ardizzoni, Andrea; Nanni, Patrizia; Lollini, Pier-Luigi; Palladini, Arianna | 2021-01-01 | CANCERS | - | 1.01 Articolo in rivista | CD38 cancers-13-00309-v2.pdf |
| Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations | Nanni, Patrizia; Landuzzi, Lorena; Manara, Maria Cristina; Righi, Alberto; Nicoletti, Giordano; C...ristalli, Camilla; Pasello, Michela; Parra, Alessandro; Carrabotta, Marianna; Ferracin, Manuela; Palladini, Arianna; Ianzano, Marianna L; Giusti, Veronica; Ruzzi, Francesca; Magnani, Mauro; Donati, Davide Maria; Picci, Piero; Lollini, Pier-Luigi; Scotlandi, Katia | 2019-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | PDX bone Sci Rep.pdf |