SEGHETTI, FRANCESCA
SEGHETTI, FRANCESCA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Dottorandi
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery.
2020 Seghetti F., Di Martino R.M.C., Catanzaro E., Bisi A., Gobbi S., Rampa A., Canonico B., Montanari M., Krysko D.V., Papa S., Fimognari C., Belluti F.
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
2022 Salerno, Alessandra; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Testi, Eleonora; Guardigni, Melissa; Roberti, Marinella; Milelli, Andrea; Bolognesi, Maria Laura
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis
2024 Exertier, Cécile; Salerno, Alessandra; Antonelli, Lorenzo; Fiorillo, Annarita; Ocello, Riccardo; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Masetti, Matteo; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Ilari, Andrea; Bolognesi, Maria Laura
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds
2022 Seghetti, Francesca; Belluti, Federica; Rampa, Angela; Gobbi, Silvia; Legac, Jenny; Parapini, Silvia; Basilico, Nicoletta; Bisi, Alessandra
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent
2019 Catanzaro E.; Seghetti F.; Calcabrini C.; Rampa A.; Gobbi S.; Sestili P.; Turrini E.; Maffei F.; Hrelia P.; Bisi A.; Belluti F.; Fimognari C.
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology
2022 Seghetti F.; Gobbi S.; Belluti F.; Rampa A.; Bisi A.
Modulation of Amyloid β-induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues
2022 De Lorenzi E.; Contardi C.; Serra M.; Bisceglia F.; Franceschini D.; Pagetta A.; Zusso M.; Di Martino R.M.C.; Seghetti F.; Belluti F.
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation
2020 Di Martino R.M.C.; Bottegoni G.; Seghetti F.; Russo D.; Penna I.; De Simone A.; Ottonello G.; Mandrup Bertozzi S.; Armirotti A.; Bandiera T.; Belluti F.; Cavalli A.
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease
2020 Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; Ana Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti
Prenylated Curcumin Analogues as Multipotent Tools to Tackle Alzheimer's Disease
2019 Bisceglia F.; Seghetti F.; Serra M.; Zusso M.; Gervasoni S.; Verga L.; Vistoli G.; Lanni C.; Catanzaro M.; De Lorenzi E.; Belluti F.
Selectivity in multiple multicomponent reactions: Types and synthetic applications
2019 Ghashghaei O.; Seghetti F.; Lavilla R.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
2023 De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena
The Keap1/Nrf2-ARE pathway as a pharmacological target for chalcones
2018 de Freitas Silva M, Pruccoli L, Morroni F, Sita G, Seghetti F, Viegas C, Tarozzi A
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. | Seghetti F., Di Martino R.M.C., Catanzaro E., Bisi A., Gobbi S., Rampa A., Canonico B., Montanari... M., Krysko D.V., Papa S., Fimognari C., Belluti F. | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | Molecules_2020_Curcumins.pdf |
| Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One | Salerno, Alessandra; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Testi, Eleonora; Gua...rdigni, Melissa; Roberti, Marinella; Milelli, Andrea; Bolognesi, Maria Laura | 2022-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | acs.jmedchem.2c00302.pdf |
| Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis | Exertier, Cécile; Salerno, Alessandra; Antonelli, Lorenzo; Fiorillo, Annarita; Ocello, Riccardo; ...Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Masetti, Matteo; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Ilari, Andrea; Bolognesi, Maria Laura | 2024-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | exertier-et-al-2024-fragment-merging-growing-and-linking-identify-new-trypanothione-reductase-inhibitors-for.pdf; jm3c01439_si_001.pdf |
| Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds | Seghetti, Francesca; Belluti, Federica; Rampa, Angela; Gobbi, Silvia; Legac, Jenny; Parapini, Sil...via; Basilico, Nicoletta; Bisi, Alessandra | 2022-01-01 | FUTURE MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent | Catanzaro E.; Seghetti F.; Calcabrini C.; Rampa A.; Gobbi S.; Sestili P.; Turrini E.; Maffei F.; ...Hrelia P.; Bisi A.; Belluti F.; Fimognari C. | 2019-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology | Seghetti F.; Gobbi S.; Belluti F.; Rampa A.; Bisi A. | 2022-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Seghetti 2022 postprint IRIS.pdf |
| Modulation of Amyloid β-induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues | De Lorenzi E.; Contardi C.; Serra M.; Bisceglia F.; Franceschini D.; Pagetta A.; Zusso M.; Di Mar...tino R.M.C.; Seghetti F.; Belluti F. | 2022-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-23-04381-v3.pdf |
| Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation | Di Martino R.M.C.; Bottegoni G.; Seghetti F.; Russo D.; Penna I.; De Simone A.; Ottonello G.; Man...drup Bertozzi S.; Armirotti A.; Bandiera T.; Belluti F.; Cavalli A. | 2020-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease | Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; An...a Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti | 2020-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | cn0c00363.pdf; cn0c00363_si_001.pdf |
| Prenylated Curcumin Analogues as Multipotent Tools to Tackle Alzheimer's Disease | Bisceglia F.; Seghetti F.; Serra M.; Zusso M.; Gervasoni S.; Verga L.; Vistoli G.; Lanni C.; Cata...nzaro M.; De Lorenzi E.; Belluti F. | 2019-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | Prenylated Curcumin acccept.pdf |
| Selectivity in multiple multicomponent reactions: Types and synthetic applications | Ghashghaei O.; Seghetti F.; Lavilla R. | 2019-01-01 | BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold | De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; ...Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.pdf |
| The Keap1/Nrf2-ARE pathway as a pharmacological target for chalcones | de Freitas Silva M, Pruccoli L, Morroni F, Sita G, Seghetti F, Viegas C, Tarozzi A | 2018-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-23-01803-v2.pdf |