ORIENTI, ISABELLA
ORIENTI, ISABELLA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di Ia fascia
Antiproliferative and Morphological Effects of Fenretinide Lipid Nanosystems in Colon Adenocarcinoma Cells
2024 Anconelli, Lorenzo; Farioli, Francesca; Lodeserto, Pietro; Andreadi, Aikaterini; Borsetti, Francesca; Voltattorni, Manuela; Galassi, Lucrezia; Rossi, Martina; Farruggia, Giovanna; Blasi, Paolo; Orienti, Isabella
Nano-fenretinide demonstrates remarkable activity in acute promyeloid leukemia cells
2024 Farruggia G.; Anconelli L.; Galassi L.; Voltattorni M.; Rossi M.; Lodeserto P.; Blasi P.; Orienti I.
Naxitamab Activity in Neuroblastoma Cells Is Enhanced by Nanofenretinide and Nanospermidine
2023 Lucrezia Galassi; Martina Rossi; Pietro Lodeserto; Monia Lenzi; Francesca Borsetti; Manuela Voltattorni; Giovanna Farruggia; Paolo Blasi; Isabella Orienti
Fenretinide in Cancer and Neurological Disease: A Two-Face Janus Molecule
2022 Potenza RL, Lodeserto P, Orienti I
Nanospermidine in Combination with Nanofenretinide Induces Cell Death in Neuroblastoma Cell Lines
2022 Lodeserto, Pietro; Rossi, Martina; Blasi, Paolo; Farruggia, Giovanna; Orienti, Isabella
Fenretinide Beneficial Effects on Amyotrophic Lateral Sclerosis-associated SOD1 G93A Mutant Protein Toxicity: In Vitro and In Vivo Evidences
2021 Orienti I, Armida M, Dobrowolny G, Pepponi R, Sollazzini G, Pezzola A, Casola I, Musarò A, Popoli P, Potenza RL.
RARE-08. POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING
2021 Dannielle Upton, Santosh Valvi, Jie Liu, Nicole Yeung, Sandra George, Caitlin Ung, Aaminah Khan, Laura Franshaw, Anahid Ehteda, Han Shen, Isabella Orienti, Giovanna Farruggia, Patrick Reynolds, Maria Tsoli, and David Ziegler
DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)
2020 Dannielle Upton, Santosh Valvi, Jie Liu, Nicole Yeung, Sandra George, Caitlin Ung, Aaminah Khan, Laura Franshaw, Anahid Ehteda, Han Shen, Isabella Orienti, Giovanna Farruggia, Christa Nath, Patrick Reynolds, Maria Tsoli, David Ziegler
Nanomicellar Lenalidomide-Fenretinide Combination Suppresses Tumor Growth in an MYCN Amplified Neuroblastoma Tumor
2020 Orienti I.; Farruggia G.; Nguyen F.; Guan P.; Calonghi N.; Kolla V.; Chorny M.; Brodeur G.M.
Pulmonary delivery of fenretinide: A possible adjuvant treatment in COVID-19
2020 Orienti I.; Gentilomi G.A.; Farruggia G.
A cationic nanomicellar complex of the quaternary amphiphilic amine rc16+ with fenretinide as a new multitasking system for antitumor therapy
2019 Orienti I.; Cripe T.P.; Currier M.A.; Cavallari C.; Teti G.; Falconi M.
A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors
2019 Orienti I.; Francescangeli F.; De Angelis M.L.; Fecchi K.; Bongiorno-Borbone L.; Signore M.; Peschiaroli A.; Boe A.; Bruselles A.; Costantino A.; Eramo A.; Salvati V.; Sette G.; Contavalli P.; Zolla L.; Oki T.; Kitamura T.; Spada M.; Giuliani A.; Baiocchi M.; La Torre F.; Melino G.; Tartaglia M.; De Maria R.; Zeuner A.
A novel nanomicellar combination of fenretinide and lenalidomide shows marked antitumor activity in a neuroblastoma xenograft model
2019 Orienti I.; Nguyen F.; Guan P.; Kolla V.; Calonghi N.; Farruggia G.; Chorny M.; Brodeur G.M.
A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells
2019 Orienti I.; Salvati V.; Sette G.; Zucchetti M.; Bongiorno-Borbone L.; Peschiaroli A.; Zolla L.; Francescangeli F.; Ferrari M.; Matteo C.; Bello E.; Di Virgilio A.; Falchi M.; De Angelis M.L.; Baiocchi M.; Melino G.; De Maria R.; Zeuner A.; Eramo A.
Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering
2016 Focaroli, Stefano; Teti, Gabriella; Salvatore, Viviana; Orienti, Isabella; Falconi, Mirella
Preparation and Evaluation of a Novel Class of Amphiphilic Amines as Antitumor Agents and Nanocarriers for Bioactive Molecules
2016 Orienti, Isabella; Falconi, Mirella; Teti, Gabriella; Currier, Mark A.; Wang, Jiang; Phelps, Mitch; Cripe, Timothy P.
Albumin nanocapsules containing fenretinide: pre-clinical evaluation of cytotoxic activity in experimental models of human non-small cell lung cancer.
2015 Pignatta S;Orienti I;Falconi M;Teti G;Arienti C;Medri L;Zanoni M;Carloni S;Zoli W;Amadori D;Tesei A
Resistance to the atypical retinoid ST1926 in SK-N-AS cells selected the subline rAS-ST with enhanced sensitivity to ATRA mediated by not conventional mechanisms: DNA damage, G2 accumulation and late telomerase inhibition
2015 Di Francesco, A.M; Cusano, G.; Franzese, O.; Orienti, I.; Falconi, M.; Vesci, L.; Riccardi, R.
Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model.
2014 Durante S; Orienti I; Teti G; Salvatore V; Focaroli S; Tesei A; Pignatta S; Falconi M.
Novel PLA microspheres with hydrophilic and bioadhesive surfaces for the controlled delivery of fenretinide
2014 Falconi M;Focaroli S;Teti G;Salvatore V;Durante S;Nicolini B;Orienti I
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Antiproliferative and Morphological Effects of Fenretinide Lipid Nanosystems in Colon Adenocarcinoma Cells | Anconelli, Lorenzo; Farioli, Francesca; Lodeserto, Pietro; Andreadi, Aikaterini; Borsetti, France...sca; Voltattorni, Manuela; Galassi, Lucrezia; Rossi, Martina; Farruggia, Giovanna; Blasi, Paolo; Orienti, Isabella | 2024-01-01 | PHARMACEUTICS | - | 1.01 Articolo in rivista | - |
| Nano-fenretinide demonstrates remarkable activity in acute promyeloid leukemia cells | Farruggia G.; Anconelli L.; Galassi L.; Voltattorni M.; Rossi M.; Lodeserto P.; Blasi P.; Orienti I. | 2024-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | Scientific_Reports 14 (2024) Article 13737.pdf; SI_Scientific_Reports 14 (2024) Article 13737.docx |
| Naxitamab Activity in Neuroblastoma Cells Is Enhanced by Nanofenretinide and Nanospermidine | Lucrezia Galassi; Martina Rossi; Pietro Lodeserto; Monia Lenzi; Francesca Borsetti; Manuela Volta...ttorni; Giovanna Farruggia; Paolo Blasi; Isabella Orienti | 2023-01-01 | PHARMACEUTICS | - | 1.01 Articolo in rivista | Pharmaceutics 15 (2023) Article 648.pdf; pharmaceutics-15-00648-s001.zip |
| Fenretinide in Cancer and Neurological Disease: A Two-Face Janus Molecule | Potenza RL, Lodeserto P, Orienti I | 2022-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-23-07426.pdf |
| Nanospermidine in Combination with Nanofenretinide Induces Cell Death in Neuroblastoma Cell Lines | Lodeserto, Pietro; Rossi, Martina; Blasi, Paolo; Farruggia, Giovanna; Orienti, Isabella | 2022-01-01 | PHARMACEUTICS | - | 1.01 Articolo in rivista | Pharmaceutics 14 (2022) 1215.pdf |
| Fenretinide Beneficial Effects on Amyotrophic Lateral Sclerosis-associated SOD1 G93A Mutant Protein Toxicity: In Vitro and In Vivo Evidences | Orienti I, Armida M, Dobrowolny G, Pepponi R, Sollazzini G, Pezzola A, Casola I, Musarò A, Popoli... P, Potenza RL. | 2021-01-01 | NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| RARE-08. POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING | Dannielle Upton, Santosh Valvi, Jie Liu, Nicole Yeung, Sandra George, Caitlin Ung, Aaminah Khan, ...Laura Franshaw, Anahid Ehteda, Han Shen, Isabella Orienti, Giovanna Farruggia, Patrick Reynolds, Maria Tsoli, and David Ziegler | 2021-01-01 | NEURO-ONCOLOGY | - | 1.06 Abstract in rivista | - |
| DIPG-07. HIGH THROUGHPUT DRUG SCREENING IDENTIFIES POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs) | Dannielle Upton, Santosh Valvi, Jie Liu, Nicole Yeung, Sandra George, Caitlin Ung, Aaminah Khan, ...Laura Franshaw, Anahid Ehteda, Han Shen, Isabella Orienti, Giovanna Farruggia, Christa Nath, Patrick Reynolds, Maria Tsoli, David Ziegler | 2020-01-01 | NEURO-ONCOLOGY | - | 1.06 Abstract in rivista | - |
| Nanomicellar Lenalidomide-Fenretinide Combination Suppresses Tumor Growth in an MYCN Amplified Neuroblastoma Tumor | Orienti I.; Farruggia G.; Nguyen F.; Guan P.; Calonghi N.; Kolla V.; Chorny M.; Brodeur G.M. | 2020-01-01 | INTERNATIONAL JOURNAL OF NANOMEDICINE | - | 1.01 Articolo in rivista | ijn-15-6873.pdf |
| Pulmonary delivery of fenretinide: A possible adjuvant treatment in COVID-19 | Orienti I.; Gentilomi G.A.; Farruggia G. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-21-03812.pdf |
| A cationic nanomicellar complex of the quaternary amphiphilic amine rc16+ with fenretinide as a new multitasking system for antitumor therapy | Orienti I.; Cripe T.P.; Currier M.A.; Cavallari C.; Teti G.; Falconi M. | 2019-01-01 | CURRENT DRUG DELIVERY | - | 1.01 Articolo in rivista | - |
| A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors | Orienti I.; Francescangeli F.; De Angelis M.L.; Fecchi K.; Bongiorno-Borbone L.; Signore M.; Pesc...hiaroli A.; Boe A.; Bruselles A.; Costantino A.; Eramo A.; Salvati V.; Sette G.; Contavalli P.; Zolla L.; Oki T.; Kitamura T.; Spada M.; Giuliani A.; Baiocchi M.; La Torre F.; Melino G.; Tartaglia M.; De Maria R.; Zeuner A. | 2019-01-01 | CELL DEATH & DISEASE | - | 1.01 Articolo in rivista | 41419_2019_Article_1775(1).pdf |
| A novel nanomicellar combination of fenretinide and lenalidomide shows marked antitumor activity in a neuroblastoma xenograft model | Orienti I.; Nguyen F.; Guan P.; Kolla V.; Calonghi N.; Farruggia G.; Chorny M.; Brodeur G.M. | 2019-01-01 | DRUG DESIGN, DEVELOPMENT AND THERAPY | - | 1.01 Articolo in rivista | dddt-13-4305.pdf |
| A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells | Orienti I.; Salvati V.; Sette G.; Zucchetti M.; Bongiorno-Borbone L.; Peschiaroli A.; Zolla L.; F...rancescangeli F.; Ferrari M.; Matteo C.; Bello E.; Di Virgilio A.; Falchi M.; De Angelis M.L.; Baiocchi M.; Melino G.; De Maria R.; Zeuner A.; Eramo A. | 2019-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | 13046_2019_Article_1383.pdf |
| Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering | Focaroli, Stefano; Teti, Gabriella; Salvatore, Viviana; Orienti, Isabella; Falconi, Mirella | 2016-01-01 | STEM CELLS INTERNATIONAL | - | 1.01 Articolo in rivista | CalciumCobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering.pdf |
| Preparation and Evaluation of a Novel Class of Amphiphilic Amines as Antitumor Agents and Nanocarriers for Bioactive Molecules | Orienti, Isabella; Falconi, Mirella; Teti, Gabriella; Currier, Mark A.; Wang, Jiang; Phelps, Mitc...h; Cripe, Timothy P. | 2016-01-01 | PHARMACEUTICAL RESEARCH | - | 1.01 Articolo in rivista | - |
| Albumin nanocapsules containing fenretinide: pre-clinical evaluation of cytotoxic activity in experimental models of human non-small cell lung cancer. | Pignatta S;Orienti I;Falconi M;Teti G;Arienti C;Medri L;Zanoni M;Carloni S;Zoli W;Amadori D;Tesei A | 2015-01-01 | NANOMEDICINE | - | 1.01 Articolo in rivista | - |
| Resistance to the atypical retinoid ST1926 in SK-N-AS cells selected the subline rAS-ST with enhanced sensitivity to ATRA mediated by not conventional mechanisms: DNA damage, G2 accumulation and late telomerase inhibition | Di Francesco, A.M; Cusano, G.; Franzese, O.; Orienti, I.; Falconi, M.; Vesci, L.; Riccardi, R. | 2015-01-01 | TOXICOLOGY IN VITRO | - | 1.01 Articolo in rivista | - |
| Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model. | Durante S; Orienti I; Teti G; Salvatore V; Focaroli S; Tesei A; Pignatta S; Falconi M. | 2014-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Novel PLA microspheres with hydrophilic and bioadhesive surfaces for the controlled delivery of fenretinide | Falconi M;Focaroli S;Teti G;Salvatore V;Durante S;Nicolini B;Orienti I | 2014-01-01 | JOURNAL OF MICROENCAPSULATION | - | 1.01 Articolo in rivista | - |