SOVERINI, SIMONA
SOVERINI, SIMONA
DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE
Docenti di ruolo di IIa fascia
Simona Soverini; SOVERINI S.; Soverini Simona; S. SOVERINI
14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia
2015-01-01 Mancini, Manuela; Leo, Elisa; Takemaru, Ken-Ichi; Campi, Virginia; Castagnetti, Fausto; Soverini, Simona; De Benedittis, Caterina; Rosti, Gianantonio; Cavo, Michele; Santucci, Maria Alessandra; Martinelli, Giovanni
A polymorphism in the chromosome 9p21 ANRIL locus is associated to Philadelphia positive acute lymphoblastic leukemia
2011-01-01 IACOBUCCI I.; SAZZINI M.; GARAGNANI P.; FERRARI A.; BOATTINI A.; LONETTI A.; PAPAYANNIDIS C.; MANTOVANI V.; MARASCO E.; OTTAVIANI E.; SOVERINI S.; GIRELLI D.; LUISELLI D.; VIGNETTI M.; BACCARANI M.; MARTINELLI G.
A POLYMORPHISM IN THE CHROMOSOME 9P21 ANRIL LOCUS IS ASSOCIATED TO PHILADELPHIA POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA SUSCEPTIBILITY
2010-01-01 Iacobucci I; Sazzini M; Ferrari A; Lonetti A; Boattini A; Papayannidis C; Garagnani P; Abbenante M; Mantovani V; Marasco E; Ottaviani E; Paolini S; Guadagnuolo V; Girelli D; Vignetti M; Pane F; Soverini S; Baccarani M; Martinelli G
A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium
2015-01-01 Simonetti, Giorgia; Padella, Antonella; FARIA DO VALLE, Italo; Manfrini, Marco; Papayannidis, Cristina; Baldazzi, Carmen; Fontana, MARIA CHIARA; Guadagnuolo, Viviana; Ferrari, Anna; Zago, Elisa; Garonzi, Marianna; Bernardi, Simona; Ottaviani, Emanuela; Astolfi, Annalisa; Abbenante, Mariachiara; Marconi, Giovanni; Soverini, Simona; Cavo, Michele; Testoni, Nicoletta; Ferrarini, Alberto; Delledonne, Massimo; Haferlach, Torsten; Remondini, Daniel; Iacobucci, Ilaria; Martinelli, Giovanni
ABCB1 polymorphisms predict imatinib response in chronic myeloid leukemia patients: a systematic review and meta-analysis.
2014-01-01 Zheng Q;Wu H;Yu Q;Kim DH;Lipton JH;Angelini S;Soverini S;Vivona D;Takahashi N;Cao J
ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: a study by the GIMEMA Working Party on Chronic Myeloid Leukemia
2005-01-01 Soverini S; Martinelli G; Rosti G; Bassi S; Amabile M; Poerio A; Giannini B; Trabacchi E; Castagnetti F; Testoni N; Luatti S; de Vivo A; Cilloni D; Izzo B; Fava M; Abruzzese E; Alberti D; Pane F; Saglio G; Baccarani M.
Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients.
2006-01-01 Iacobucci I; Saglio G; Rosti G; Testoni N; Pane F; Amabile M; Poerio A; Soverini S; Bassi S; Cilloni D; Bassan R; Breccia M; Lauria F; Izzo B; Merante S; Frassoni F; Paolini S; Montefusco E; Baccarani M; Martinelli G
ACTIVATION-INDUCED CYTIDINE DEAMINASE IS ABERRANTLY OVEREXPRESSED IN BCRABL1 POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA CELLS AND PROMOTES DNA-SINGLE STRAND BREAKS
2008-01-01 Iacobucci I; Lonetti A;; Ferrari A; Soverini S; Ottaviani E; Testoni N; Colarossi S; Salmi F; Gnani A; Paolini S; Piccaluga PP; Papayannidis C; Panagiota G; Cilloni D; Messa F;; Pane F; Vitale A; Chiaretti S; Saglio G; Foà R; Baccarani M; Martinelli G
Adult B-Cell Precursor Acute Lymphoblastic Leukemia (BC-ALL) Negative For Recurrent Fusion Genes Are Characterized By a High Complex Genetic Heterogeneity Influencing Prognosis
2013-01-01 Iacobucci, Ilaria; Ferrari, Anna; Perricone, Margherita; Robustelli, Valentina; Papayannidis, Cristina; Zuntini, Roberta; Maria Chiara Abbenante, ; Venturi, Claudia; Baldazzi, Carmen; Ottaviani, Emanuela; Giannini, Barbara; Ghelli Luserna Di Rorà, Andrea; Lonetti, Annalisa; Vitale, Antonella; Elia, Loredana; Guadagnuolo, Viviana; Testoni, Nicoletta; Soverini, Simona; Paolini, Stefania; Parisi, Sarah; Sartor, Chiara; Cattina, Federica; Russo, Domenico; Foà, Robin; Chiaretti, Sabina; Kohlmann, Alexander; Martinelli, Giovanni
Advances in the biology and therapy of chronic myeloid leukemia (CML): Proceedings from the 6(th) Post-ASH International CML and Myeloproliferative Neoplasms Workshop.
2013-01-01 van Etten R.A.; Mauro M.; Radich J.P.; Goldman J.M.; Saglio G.; Jamieson C.; Soverini S.; Gambacorti-Passerini C.; Hehlmann R.; Martinelli G.; Perrotti D.; Scadden D.T.; Skorski T.; Tefferi A.; Mughal T.I.
Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr–Abl mutations and mutational analysis
2012-01-01 Soverini S; Martinelli G.; Rosti G.; Iacobucci I.; Baccarani M.
AID EXPRESSION IN BCR/ABL POSITIVE ALL IS ASSOCIATED WITH A PECULIAR GENE EXPRESSION PROFILE AND DEREGULATION OF DNA REPAIR AND REPLICATION GENES
2009-01-01 M. Messina; S. Chiaretti; I. Iacobucci; S. Tavolaro; A. Vitale; I. Della Starza; A. Lonetti; C. Papayannidis; A.D. Negulici; S. Soverini; D. Cilloni; A. Guarini; G. Martinelli; R. Foà
Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias.
2011-01-01 Nicolini F.E.; Basak G.W.; Soverini S.; Martinelli G.; Mauro M.J.; Müller M.C.; Hochhaus A.; Chuah C.; Dufva I.H.; Rege-Cambrin G.; Saglio G.; Michallet M.; Labussière H.; Morisset S.; Hayette S.; Etienne G.; Olavarria E.; Zhou W.; Peter S.; Apperley J.F.; Cortes J.
Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)
2016-01-01 Marconi, Giovanni; Papayannidis, Cristina; Fontana, MARIA CHIARA; Padella, Antonella; Simonetti, Giorgia; Manfrini, Marco; Ferrari, Anna; Franchini, Eugenia; Paolini, Stefania; Parisi, Sarah; Sartor, Chiara; Abbenante, Mariachiara; LO MONACO, Silvia; Volpato, Francesca; Tenti, Elena; Guadagnuolo, Viviana; Perricone, Margherita; Bochicchio, MARIA TERESA; GHELLI LUSERNA DI RORÀ, Andrea; Baldazzi, Carmen; Robustelli, Valentina; Testoni, Nicoletta; Soverini, Simona; Ottaviani, Emanuela; Martinelli, Giovanni
ALTERNATIVE SPLICING OF IKAROS mRNA IS RESPONSIBLE FOR THE EXPRESSION OF DIFFERENT ABERRANT ISOFORMS IN PHILADELPHIA CHROMOSOME-POSITIVE (PH+) ADULT ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL) PATIENTS
2008-01-01 A. Lonetti; I. Iacobucci; R. Zuntini; S. Ferrari; D. Cilloni; F. Messa; E. Ottaviani; F. Arruga; F. Salmi; S. Paolini; C. Papayannidis; P.P. Piccaluga; P. Giannoulia; S. Soverini; G. Saglio; F. Pane; A. Vitale; S. Chiaretti; R. Foà; M. Baccarani; G. Martinelli
Analisi di polimorfismi in geni coinvolti nel ciclo dei folati come determinanti di suscettibilità a leucemia mieloide cronica.
2009-01-01 TURRINI E.; S. ANGELINI; S. SOVERINI; M. BACCARANI; G. CANTELLI FORTI; P. HRELIA
Analysis of Bone Marrow Microenviroment Factors As Early Markers of Response in Patients with Newly Diagnosed Bcr-Abl Positive CML in Chronic Phase Treated with Nilotinib
2012-01-01 Concetta Quintarelli; Biagio De Angelis; Santa Errichiello; Simona Caruso; Nicola Esposito; Luigia Luciano; Simona Paratore; Claudia Galimberti; Simona Soverini; Carolina Terragna; Daniela Cilloni; Giuseppe Saglio; Giovanni Martinelli; Frank Giles; Andreas Hochhaus; Fabrizio Pane
Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation.
2008-01-01 Monteghirfo S.; Tosetti F.; Ambrosini C.; Stigliani S.; Pozzi S.; Frassoni F.; Fassina G.; Soverini S.; Albini A.; Ferrari N.
Application of the whole-transcriptome shotgun sequencing approach to the study of Philadelphia-positive acute lymphoblastic leukemia
2012-01-01 Iacobucci I.; Ferrarini A.; Sazzini M.; Giacomelli E.; Lonetti A.; Xumerle L.; Ferrari A.; Papayannidis C.; Malerba G.; Luiselli D.; Boattini A.; Garagnani P.; Vitale A.; Soverini S.; Pane F.; Baccarani M.; Delledonne M.; Martinelli G.
ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112
2011-01-01 I Iacobucci; F Cattina; S Pomella; A Lonetti; A Ferrari; C Papayannidis; S Trino; D Erriquez; V Guadagnuolo; E Ottaviani; S Formica; S Soverini; F Paoloni; M Vignetti; D Russo; G Perini; M Baccarani; G Martinelli
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| 14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia | Mancini, Manuela; Leo, Elisa; Takemaru, Ken-Ichi; Campi, Virginia; Castagnetti, Fausto; Soverini,... Simona; De Benedittis, Caterina; Rosti, Gianantonio; Cavo, Michele; Santucci, Maria Alessandra; Martinelli, Giovanni | 2015-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | Mancini_PONE_2015.pdf; pone.0131074.s001.pdf; pone.0131074.s002.pdf; pone.0131074.s003.pdf; pone.0131074.s004.pdf; pone.0131074.s004.pdf |
| A polymorphism in the chromosome 9p21 ANRIL locus is associated to Philadelphia positive acute lymphoblastic leukemia | IACOBUCCI I.; SAZZINI M.; GARAGNANI P.; FERRARI A.; BOATTINI A.; LONETTI A.; PAPAYANNIDIS C.; MAN...TOVANI V.; MARASCO E.; OTTAVIANI E.; SOVERINI S.; GIRELLI D.; LUISELLI D.; VIGNETTI M.; BACCARANI M.; MARTINELLI G. | 2011-01-01 | LEUKEMIA RESEARCH | - | 1.01 Articolo in rivista | - |
| A POLYMORPHISM IN THE CHROMOSOME 9P21 ANRIL LOCUS IS ASSOCIATED TO PHILADELPHIA POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA SUSCEPTIBILITY | Iacobucci I; Sazzini M; Ferrari A; Lonetti A; Boattini A; Papayannidis C; Garagnani P; Abbenante ...M; Mantovani V; Marasco E; Ottaviani E; Paolini S; Guadagnuolo V; Girelli D; Vignetti M; Pane F; Soverini S; Baccarani M; Martinelli G | 2010-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium | Simonetti, Giorgia; Padella, Antonella; FARIA DO VALLE, Italo; Manfrini, Marco; Papayannidis, Cri...stina; Baldazzi, Carmen; Fontana, MARIA CHIARA; Guadagnuolo, Viviana; Ferrari, Anna; Zago, Elisa; Garonzi, Marianna; Bernardi, Simona; Ottaviani, Emanuela; Astolfi, Annalisa; Abbenante, Mariachiara; Marconi, Giovanni; Soverini, Simona; Cavo, Michele; Testoni, Nicoletta; Ferrarini, Alberto; Delledonne, Massimo; Haferlach, Torsten; Remondini, Daniel; Iacobucci, Ilaria; Martinelli, Giovanni | 2015-01-01 | BLOOD | - | 1.06 Abstract in rivista | - |
| ABCB1 polymorphisms predict imatinib response in chronic myeloid leukemia patients: a systematic review and meta-analysis. | Zheng Q;Wu H;Yu Q;Kim DH;Lipton JH;Angelini S;Soverini S;Vivona D;Takahashi N;Cao J | 2014-01-01 | PHARMACOGENOMICS JOURNAL | - | 1.01 Articolo in rivista | - |
| ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: a study by the GIMEMA Working Party on Chronic Myeloid Leukemia | Soverini S; Martinelli G; Rosti G; Bassi S; Amabile M; Poerio A; Giannini B; Trabacchi E; Castagn...etti F; Testoni N; Luatti S; de Vivo A; Cilloni D; Izzo B; Fava M; Abruzzese E; Alberti D; Pane F; Saglio G; Baccarani M. | 2005-01-01 | JOURNAL OF CLINICAL ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients. | Iacobucci I; Saglio G; Rosti G; Testoni N; Pane F; Amabile M; Poerio A; Soverini S; Bassi S; Cill...oni D; Bassan R; Breccia M; Lauria F; Izzo B; Merante S; Frassoni F; Paolini S; Montefusco E; Baccarani M; Martinelli G | 2006-01-01 | CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| ACTIVATION-INDUCED CYTIDINE DEAMINASE IS ABERRANTLY OVEREXPRESSED IN BCRABL1 POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA CELLS AND PROMOTES DNA-SINGLE STRAND BREAKS | Iacobucci I; Lonetti A;; Ferrari A; Soverini S; Ottaviani E; Testoni N; Colarossi S; Salmi F; Gna...ni A; Paolini S; Piccaluga PP; Papayannidis C; Panagiota G; Cilloni D; Messa F;; Pane F; Vitale A; Chiaretti S; Saglio G; Foà R; Baccarani M; Martinelli G | 2008-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| Adult B-Cell Precursor Acute Lymphoblastic Leukemia (BC-ALL) Negative For Recurrent Fusion Genes Are Characterized By a High Complex Genetic Heterogeneity Influencing Prognosis | Iacobucci, Ilaria; Ferrari, Anna; Perricone, Margherita; Robustelli, Valentina; Papayannidis, Cri...stina; Zuntini, Roberta; Maria Chiara Abbenante, ; Venturi, Claudia; Baldazzi, Carmen; Ottaviani, Emanuela; Giannini, Barbara; Ghelli Luserna Di Rorà, Andrea; Lonetti, Annalisa; Vitale, Antonella; Elia, Loredana; Guadagnuolo, Viviana; Testoni, Nicoletta; Soverini, Simona; Paolini, Stefania; Parisi, Sarah; Sartor, Chiara; Cattina, Federica; Russo, Domenico; Foà, Robin; Chiaretti, Sabina; Kohlmann, Alexander; Martinelli, Giovanni | 2013-01-01 | BLOOD | - | 4.02 Riassunto (Abstract) | - |
| Advances in the biology and therapy of chronic myeloid leukemia (CML): Proceedings from the 6(th) Post-ASH International CML and Myeloproliferative Neoplasms Workshop. | van Etten R.A.; Mauro M.; Radich J.P.; Goldman J.M.; Saglio G.; Jamieson C.; Soverini S.; Gambaco...rti-Passerini C.; Hehlmann R.; Martinelli G.; Perrotti D.; Scadden D.T.; Skorski T.; Tefferi A.; Mughal T.I. | 2013-01-01 | LEUKEMIA & LYMPHOMA | - | 1.01 Articolo in rivista | - |
| Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr–Abl mutations and mutational analysis | Soverini S; Martinelli G.; Rosti G.; Iacobucci I.; Baccarani M. | 2012-01-01 | PHARMACOGENOMICS | - | 1.01 Articolo in rivista | - |
| AID EXPRESSION IN BCR/ABL POSITIVE ALL IS ASSOCIATED WITH A PECULIAR GENE EXPRESSION PROFILE AND DEREGULATION OF DNA REPAIR AND REPLICATION GENES | M. Messina; S. Chiaretti; I. Iacobucci; S. Tavolaro; A. Vitale; I. Della Starza; A. Lonetti; C. P...apayannidis; A.D. Negulici; S. Soverini; D. Cilloni; A. Guarini; G. Martinelli; R. Foà | 2009-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias. | Nicolini F.E.; Basak G.W.; Soverini S.; Martinelli G.; Mauro M.J.; Müller M.C.; Hochhaus A.; Chua...h C.; Dufva I.H.; Rege-Cambrin G.; Saglio G.; Michallet M.; Labussière H.; Morisset S.; Hayette S.; Etienne G.; Olavarria E.; Zhou W.; Peter S.; Apperley J.F.; Cortes J. | 2011-01-01 | BLOOD | - | 1.01 Articolo in rivista | - |
| Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML) | Marconi, Giovanni; Papayannidis, Cristina; Fontana, MARIA CHIARA; Padella, Antonella; Simonetti, ...Giorgia; Manfrini, Marco; Ferrari, Anna; Franchini, Eugenia; Paolini, Stefania; Parisi, Sarah; Sartor, Chiara; Abbenante, Mariachiara; LO MONACO, Silvia; Volpato, Francesca; Tenti, Elena; Guadagnuolo, Viviana; Perricone, Margherita; Bochicchio, MARIA TERESA; GHELLI LUSERNA DI RORÀ, Andrea; Baldazzi, Carmen; Robustelli, Valentina; Testoni, Nicoletta; Soverini, Simona; Ottaviani, Emanuela; Martinelli, Giovanni | 2016-01-01 | BLOOD | - | 1.06 Abstract in rivista | - |
| ALTERNATIVE SPLICING OF IKAROS mRNA IS RESPONSIBLE FOR THE EXPRESSION OF DIFFERENT ABERRANT ISOFORMS IN PHILADELPHIA CHROMOSOME-POSITIVE (PH+) ADULT ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL) PATIENTS | A. Lonetti; I. Iacobucci; R. Zuntini; S. Ferrari; D. Cilloni; F. Messa; E. Ottaviani; F. Arruga; ...F. Salmi; S. Paolini; C. Papayannidis; P.P. Piccaluga; P. Giannoulia; S. Soverini; G. Saglio; F. Pane; A. Vitale; S. Chiaretti; R. Foà; M. Baccarani; G. Martinelli | 2008-01-01 | HAEMATOLOGICA | - | 4.02 Riassunto (Abstract) | - |
| Analisi di polimorfismi in geni coinvolti nel ciclo dei folati come determinanti di suscettibilità a leucemia mieloide cronica. | TURRINI E.; S. ANGELINI; S. SOVERINI; M. BACCARANI; G. CANTELLI FORTI; P. HRELIA | 2009-01-01 | - | Società Italiana di Tossicologia | 4.02 Riassunto (Abstract) | - |
| Analysis of Bone Marrow Microenviroment Factors As Early Markers of Response in Patients with Newly Diagnosed Bcr-Abl Positive CML in Chronic Phase Treated with Nilotinib | Concetta Quintarelli; Biagio De Angelis; Santa Errichiello; Simona Caruso; Nicola Esposito; Luigi...a Luciano; Simona Paratore; Claudia Galimberti; Simona Soverini; Carolina Terragna; Daniela Cilloni; Giuseppe Saglio; Giovanni Martinelli; Frank Giles; Andreas Hochhaus; Fabrizio Pane | 2012-01-01 | BLOOD | - | 4.02 Riassunto (Abstract) | - |
| Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation. | Monteghirfo S.; Tosetti F.; Ambrosini C.; Stigliani S.; Pozzi S.; Frassoni F.; Fassina G.; Soveri...ni S.; Albini A.; Ferrari N. | 2008-01-01 | MOLECULAR CANCER THERAPEUTICS | - | 1.01 Articolo in rivista | - |
| Application of the whole-transcriptome shotgun sequencing approach to the study of Philadelphia-positive acute lymphoblastic leukemia | Iacobucci I.; Ferrarini A.; Sazzini M.; Giacomelli E.; Lonetti A.; Xumerle L.; Ferrari A.; Papaya...nnidis C.; Malerba G.; Luiselli D.; Boattini A.; Garagnani P.; Vitale A.; Soverini S.; Pane F.; Baccarani M.; Delledonne M.; Martinelli G. | 2012-01-01 | BLOOD CANCER JOURNAL | - | 1.01 Articolo in rivista | Iacobucci_BloodCancerJ2012.pdf |
| ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112 | I Iacobucci; F Cattina; S Pomella; A Lonetti; A Ferrari; C Papayannidis; S Trino; D Erriquez; V G...uadagnuolo; E Ottaviani; S Formica; S Soverini; F Paoloni; M Vignetti; D Russo; G Perini; M Baccarani; G Martinelli | 2011-01-01 | BLOOD | - | 4.02 Riassunto (Abstract) | - |