Sfoglia per Autore
Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NF-kB.
2012 Leoni V.; Gianni T.; Salvioli S.; Campadelli-Fiume G.
Herpesviruses as oncolytic agents
2012 Campadelli-Fiume G.; Menotti L.; Zhou G.; De Giovanni C.; Nanni P.; Lollini P.-L.
Type I Interferon and NF- B Activation Elicited by Herpes Simplex Virus gH/gL via v 3 Integrin in Epithelial and Neuronal Cell Lines
2013 T. Gianni;V. Leoni;G. Campadelli-Fiume
Preclinical therapy of disseminated HER-2+ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.
2013 P. Nanni; V. Gatta; L. Menotti; C. De Giovanni; M. Ianzano; A. Palladini; V. Grosso; M. Dall’Ora; S. Croci; G. Nicoletti; L. Landuzzi; M. Iezzi; G. Campadelli-Fiume; P.-L. Lollini.
αvβ6- and αvβ8-Integrins Serve As Interchangeable Receptors for HSV gH/gL to Promote Endocytosis and Activation of Membrane Fusion
2013 Tatiana Gianni; Stefano Salvioli; Liudmila S. Chesnokova; Lindsey M. Hutt-Fletcher; Gabriella Campadelli-Fiume
The Epithelial αvβ3-Integrin Boosts the MYD88-Dependent TLR2 Signaling in Response to Viral and Bacterial Components
2014 Gianni, T; Campadelli-Fiume, G.
The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its Receptors
2015 Gatta, Valentina; Petrovic, Biljana; Campadelli-Fiume, Gabriella
Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry
2015 Gianni, T.; Massaro, R.; Campadelli-Fiume, G.
Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases
2015 Leoni, Valerio; Gatta, Valentina; Palladini, Arianna; Nicoletti, Giordano; Ranieri, Dario; Dall'Ora, Massimiliano; Grosso, Valentina; Rossi, Martina; Alviano, Francesco; Bonsi, Laura; Nanni, Patrizia; Lollini, Pier-Luigi; Campadelli-Fiume, Gabriella
αvβ3 Integrin boosts the innate immune response elicited in epithelial cells through plasma membrane and endosomal Toll-like receptors
2016 Casiraghi, Costanza; Gianni, Tatiana; Campadelli-Fiume, Gabriella
Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome
2016 Campadelli, MARIA GABRIELLA; Collins Mcmillen, Donna; Gianni, Tatiana; Yurochko, Andrew D.
Retargeting strategies for oncolytic herpes simplex viruses
2016 Campadelli, MARIA GABRIELLA; Petrovic, Biljana; Leoni, Valerio; Gianni, Tatiana; Avitabile, Elisa; Casiraghi, Costanza; Gatta, Valentina
Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins
2017 Petrovic, Biljana; Gianni, Tatiana; Gatta, Valentina; Campadelli-Fiume, Gabriella*
A strategy for cultivation of retargeted oncolytic herpes simplex viruses in non-cancer cells
2017 Leoni, Valerio; Gatta, Valentina; Casiraghi, Costanza; Nicosia, Alfredo; Petrovic, Biljana; Campadelli-Fiume, Gabriella
Immunocompetent C57BL/6 mouse, engineered to be tolerant to the human HER2 receptor, as a model for the study of retargeted fully-virulent oncolytic Herpes Virus (HSV)
2018 Sanapo M., Barboni C., Campadelli-Fiume MG, Mazza F, Leoni V, Zaghini A
The simultaneous insertion of two ligands in gD for the cultivation of oncolytic HSVs in non-cancer cells and the retargeting to cancer receptors
2018 Leoni, Valerio; Petrovic, Biljana; Gianni, Tatiana; Gatta, Valentina; Campadelli-Fiume, Gabriella
A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors
2018 Leoni, Valerio; Vannini, Andrea; Gatta, Valentina; Rambaldi, Julie; Sanapo, Mara; Barboni, Catia; Zaghini, Anna; Nanni, Patrizia; Lollini, Pier-Luigi; Casiraghi, Costanza; Campadelli-Fiume, Gabriella
Dual Ligand Insertion in gB and gD of Oncolytic Herpes Simplex Viruses for Retargeting to a Producer Vero Cell Line and to Cancer Cells
2018 Petrovic, Biljana; Leoni, Valerio; Gatta, Valentina; Zaghini, Anna; Vannini, Andrea; Campadelli-Fiume, Gabriella
HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses
2018 Menotti, Laura; Avitabile, Elisa; Gatta, Valentina; Malatesta, Paolo; Petrovic, Biljana; Campadelli-Fiume, Gabriella
αvβ3-integrin regulates PD-L1 expression and is involved in cancer immune evasion
2019 Vannini A.; Leoni V.; Barboni C.; Sanapo M.; Zaghini A.; Malatesta P.; Campadelli-Fiume G.; Gianni T.
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