MASSENZIO, FRANCESCA
MASSENZIO, FRANCESCA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Ricercatori a tempo determinato
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease
2015 Prati, Federica; De Simone, Angela; Armirotti, Andrea; Summa, Maria; Pizzirani, Daniela; Scarpelli, Rita; Bertozzi, Sine Mandrup; Perez, Daniel I.; Andrisano, Vincenza; Perez-Castillo, Ana; Monti, Barbara; Massenzio, Francesca; Polito, Letizia; Racchi, Marco; Sabatino, Piera; Bottegoni, Giovanni; Martinez, Ana; Cavalli, Andrea; Bolognesi, Maria L.
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential
2019 Uliassi, Elisa; Pena-Altamira, Luis Emiliano; Morales, Aixa V.; Massenzio, Francesca; Petralla, Sabrina; Rossi, Michele; Roberti, Marinella; Martinez Gonzalez, Loreto; Martinez, Ana; Monti, Barbara; Bolognesi, Maria Laura*
Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation.
2016 Peña-Altamira, E; Prati, F; Massenzio, F; Virgili, M; Contestabile, A; Bolognesi, Ml; Monti, B.
Cite Share Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
2018 White MA; Kim E; Duffy A; Adalbert R; Phillips BU; Peters OM; Stephenson J; Yang S; MASSENZIO F; Lin Z; Andrews S; Segonds-Pichon A; Metterville J; Saksida LM; Mead R; Ribchester RR; Barhomi Y; Serre T; Coleman MP; Fallon JR; Bussey TJ; Brown RH Jr; Sreedharan J.
Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo
2019 Petralla S.; Pena-Altamira L.E.; Poeta E.; Massenzio F.; Virgili M.; Barile S.N.; Sbano L.; Profilo E.; Corricelli M.; Danese A.; Giorgi C.; Ostan R.; Capri M.; Pinton P.; Palmieri F.; Lasorsa F.M.; Monti B.
Dietary Protein Source Influences Brain Inflammation and Memory in a Male Senescence-Accelerated Mouse Model of Dementia
2021 Sabrina Petralla, Cristina Parenti, Valentina Ravaioli, Irene Fancello, Francesca Massenzio, Marco Virgili, Barbara Monti, Emiliano Pena-Altamira
Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.
2017 Profilo, E; Peña-Altamira, Le; Corricelli, M; Castegna, A; Danese, A; Agrimi, G; Petralla, S; Giannuzzi, G; Porcelli, V; Sbano, L; Viscomi, C; Massenzio, F; Palmieri, Em; Giorgi, C; Fiermonte, G; Virgili, M; Palmieri, L; Zeviani, M; Pinton, P; Monti, B; Palmieri, F; Lasorsa, Fm.
Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease
2021 Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Maestri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei
Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches
2021 Sabrina Petralla, Francesca De Chirico, Andrea Miti, Ottavia Tartagni, Francesca Massenzio, Eleonora Poeta, Marco Virgili, Giampaolo Zuccheri, Barbara Monti
Erratum to: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD (Nature Neuroscience, (2018), 21, 4, (552-563), 10.1038/s41593-018-0113-5)
2018 White M.A.; Kim E.; Duffy A.; Adalbert R.; Phillips B.U.; Peters O.M.; Stephenson J.; Yang S.; Massenzio F.; Lin Z.; Andrews S.; Segonds-Pichon A.; Metterville J.; Saksida L.M.; Mead R.; Ribchester R.R.; Barhomi Y.; Serre T.; Coleman M.P.; Fallon J.R.; Bussey T.J.; Brown R.H.; Sreedharan J.
Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
2022 Poeta E.; Petralla S.; Babini G.; Renzi B.; Celauro L.; Magnifico M.C.; Barile S.N.; Masotti M.; De Chirico F.; Massenzio F.; Viggiano L.; Palmieri L.; Virgili M.; Lasorsa F.M.; Monti B.
In vivo morphological alterations of TAMs during KCa3.1 inhibition—by using in vivo two-photon time-lapse technology
2022 Francesca Massenzio, Marco Cambiaghi, Federica Marchiotto, Diana Boriero, Cristina Limatola, Giuseppina D’Alessandro, Mario Buffelli
Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease
2020 Losurdo, Morris; Pedrazzoli, Matteo; D'Agostino, Claudia; Elia, Chiara A.; Massenzio, Francesca; Lonati, Elena; Mauri, Mario; Rizzi, Laura; Molteni, Laura; Bresciani, Elena; Dander, Erica; D'Amico, Giovanna; Bulbarelli, Alessandra; Torsello, Antonio; Matteoli, Michela; Buffelli, Mario; Coco, Silvia
Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose
2018 Massenzio, Francesca; Peña-Altamira, Emiliano; Petralla, Sabrina; Virgili, Marco; Zuccheri, Giampaolo; Miti, Andrea; Polazzi, Elisabetta; Mengoni, Ilaria; Piffaretti, Deborah; Monti, Barbara*
Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology.
2015 Polazzi, E; Mengoni, I; Peña-Altamira, E; Massenzio, F; Virgili, M; Petralla, S; Monti, B.
New models of Parkinson’s like neuroinflammation in human microglia clone 3: Activation profiles induced by INF-γ plus high glucose and mitochondrial inhibitors
2022 Francesca De Chirico, Eleonora Poeta, Giorgia Babini, Iliana Piccolino, Barbara Monti, Francesca Massenzio*
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease
2019 Romeiro L.A.S.; Da Costa Nunes J.L.; De Oliveira Miranda C.; Simoies Heyn Roth Cardoso G.; De Oliveira A.S.; Gandini A.; Kobrlova T.; Soukup O.; Rossi Michele.; Senger J.; Jung M.; Gervasoni S.; Vistoli G.; Petralla S.; Massenzio F.; Monti B.; Bolognesi M.L.
Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.
2017 Peña-Altamira, E; Petralla, S; Massenzio, F; Virgili, M; Bolognesi, Ml; Monti, B.
Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors.
2018 Peña-Altamira LE, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, Poli A, Zuccarini M, Ciccarelli R, Di Iorio P, Virgili M, Monti B, Caciagli F.
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis
2022 Albertini, C; Salerno, A; Atzenti, S; Uliassi, E; Massenzio, F; Maruca, A; Rocca, R; Mecava, M; Silva, FSG; Mena, D; Valente, P; Duarte, AI; Chavarria, D; Bissaro, M; Moro, S; Federico, S; Spalluto, G; Soukup, O; Borges, F; Alcaro, S; Monti, B; Oliveira, PJ; Menendez, JC; Bolognesi, ML
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease | Prati, Federica; De Simone, Angela; Armirotti, Andrea; Summa, Maria; Pizzirani, Daniela; Scarpell...i, Rita; Bertozzi, Sine Mandrup; Perez, Daniel I.; Andrisano, Vincenza; Perez-Castillo, Ana; Monti, Barbara; Massenzio, Francesca; Polito, Letizia; Racchi, Marco; Sabatino, Piera; Bottegoni, Giovanni; Martinez, Ana; Cavalli, Andrea; Bolognesi, Maria L. | 2015-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | accepted11585-546374.pdf |
| A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential | Uliassi, Elisa; Pena-Altamira, Luis Emiliano; Morales, Aixa V.; Massenzio, Francesca; Petralla, S...abrina; Rossi, Michele; Roberti, Marinella; Martinez Gonzalez, Loreto; Martinez, Ana; Monti, Barbara; Bolognesi, Maria Laura* | 2019-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation. | Peña-Altamira, E; Prati, F; Massenzio, F; Virgili, M; Contestabile, A; Bolognesi, Ml; Monti, B. | 2016-01-01 | EXPERT OPINION ON THERAPEUTIC TARGETS | - | 1.01 Articolo in rivista | - |
| Cite Share Publisher Correction: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD | White MA; Kim E; Duffy A; Adalbert R; Phillips BU; Peters OM; Stephenson J; Yang S; MASSENZIO F; ...Lin Z; Andrews S; Segonds-Pichon A; Metterville J; Saksida LM; Mead R; Ribchester RR; Barhomi Y; Serre T; Coleman MP; Fallon JR; Bussey TJ; Brown RH Jr; Sreedharan J. | 2018-01-01 | NATURE NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo | Petralla S.; Pena-Altamira L.E.; Poeta E.; Massenzio F.; Virgili M.; Barile S.N.; Sbano L.; Profi...lo E.; Corricelli M.; Danese A.; Giorgi C.; Ostan R.; Capri M.; Pinton P.; Palmieri F.; Lasorsa F.M.; Monti B. | 2019-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-20-04486.pdf |
| Dietary Protein Source Influences Brain Inflammation and Memory in a Male Senescence-Accelerated Mouse Model of Dementia | Sabrina Petralla, Cristina Parenti, Valentina Ravaioli, Irene Fancello, Francesca Massenzio, Marc...o Virgili, Barbara Monti, Emiliano Pena-Altamira | 2021-01-01 | MOLECULAR NEUROBIOLOGY | - | 1.01 Articolo in rivista | - |
| Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. | Profilo, E; Peña-Altamira, Le; Corricelli, M; Castegna, A; Danese, A; Agrimi, G; Petralla, S; Gia...nnuzzi, G; Porcelli, V; Sbano, L; Viscomi, C; Massenzio, F; Palmieri, Em; Giorgi, C; Fiermonte, G; Virgili, M; Palmieri, L; Zeviani, M; Pinton, P; Monti, B; Palmieri, F; Lasorsa, Fm. | 2017-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA | - | 1.01 Articolo in rivista | - |
| Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease | Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Mae...stri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei | 2021-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches | Sabrina Petralla, Francesca De Chirico, Andrea Miti, Ottavia Tartagni, Francesca Massenzio, Eleon...ora Poeta, Marco Virgili, Giampaolo Zuccheri, Barbara Monti | 2021-01-01 | BIOMOLECULES | - | 1.01 Articolo in rivista | biomolecules-11-00306-v2.pdf |
| Erratum to: TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD (Nature Neuroscience, (2018), 21, 4, (552-563), 10.1038/s41593-018-0113-5) | White M.A.; Kim E.; Duffy A.; Adalbert R.; Phillips B.U.; Peters O.M.; Stephenson J.; Yang S.; Ma...ssenzio F.; Lin Z.; Andrews S.; Segonds-Pichon A.; Metterville J.; Saksida L.M.; Mead R.; Ribchester R.R.; Barhomi Y.; Serre T.; Coleman M.P.; Fallon J.R.; Bussey T.J.; Brown R.H.; Sreedharan J. | 2018-01-01 | NATURE NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency | Poeta E.; Petralla S.; Babini G.; Renzi B.; Celauro L.; Magnifico M.C.; Barile S.N.; Masotti M.; ...De Chirico F.; Massenzio F.; Viggiano L.; Palmieri L.; Virgili M.; Lasorsa F.M.; Monti B. | 2022-01-01 | FRONTIERS IN CELLULAR NEUROSCIENCE | - | 1.01 Articolo in rivista | fncel-15-773709.pdf |
| In vivo morphological alterations of TAMs during KCa3.1 inhibition—by using in vivo two-photon time-lapse technology | Francesca Massenzio, Marco Cambiaghi, Federica Marchiotto, Diana Boriero, Cristina Limatola, Gius...eppina D’Alessandro, Mario Buffelli | 2022-01-01 | FRONTIERS IN CELLULAR NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease | Losurdo, Morris; Pedrazzoli, Matteo; D'Agostino, Claudia; Elia, Chiara A.; Massenzio, Francesca; ...Lonati, Elena; Mauri, Mario; Rizzi, Laura; Molteni, Laura; Bresciani, Elena; Dander, Erica; D'Amico, Giovanna; Bulbarelli, Alessandra; Torsello, Antonio; Matteoli, Michela; Buffelli, Mario; Coco, Silvia | 2020-01-01 | STEM CELLS TRANSLATIONAL MEDICINE | - | 1.01 Articolo in rivista | - |
| Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose | Massenzio, Francesca; Peña-Altamira, Emiliano; Petralla, Sabrina; Virgili, Marco; Zuccheri, Giamp...aolo; Miti, Andrea; Polazzi, Elisabetta; Mengoni, Ilaria; Piffaretti, Deborah; Monti, Barbara* | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE | - | 1.01 Articolo in rivista | - |
| Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology. | Polazzi, E; Mengoni, I; Peña-Altamira, E; Massenzio, F; Virgili, M; Petralla, S; Monti, B. | 2015-01-01 | JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY | - | 1.01 Articolo in rivista | - |
| New models of Parkinson’s like neuroinflammation in human microglia clone 3: Activation profiles induced by INF-γ plus high glucose and mitochondrial inhibitors | Francesca De Chirico, Eleonora Poeta, Giorgia Babini, Iliana Piccolino, Barbara Monti, Francesca ...Massenzio* | 2022-01-01 | FRONTIERS IN CELLULAR NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease | Romeiro L.A.S.; Da Costa Nunes J.L.; De Oliveira Miranda C.; Simoies Heyn Roth Cardoso G.; De Oli...veira A.S.; Gandini A.; Kobrlova T.; Soukup O.; Rossi Michele.; Senger J.; Jung M.; Gervasoni S.; Vistoli G.; Petralla S.; Massenzio F.; Monti B.; Bolognesi M.L. | 2019-01-01 | ACS MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease. | Peña-Altamira, E; Petralla, S; Massenzio, F; Virgili, M; Bolognesi, Ml; Monti, B. | 2017-01-01 | FRONTIERS IN AGING NEUROSCIENCE | - | 1.01 Articolo in rivista | - |
| Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors. | Peña-Altamira LE, Polazzi E, Giuliani P, Beraudi A, Massenzio F, Mengoni I, Poli A, Zuccarini M, ...Ciccarelli R, Di Iorio P, Virgili M, Monti B, Caciagli F. | 2018-01-01 | NEUROCHEMISTRY INTERNATIONAL | - | 1.01 Articolo in rivista | - |
| Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis | Albertini, C; Salerno, A; Atzenti, S; Uliassi, E; Massenzio, F; Maruca, A; Rocca, R; Mecava, M; S...ilva, FSG; Mena, D; Valente, P; Duarte, AI; Chavarria, D; Bissaro, M; Moro, S; Federico, S; Spalluto, G; Soukup, O; Borges, F; Alcaro, S; Monti, B; Oliveira, PJ; Menendez, JC; Bolognesi, ML | 2022-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | acschemneuro.2c00261.pdf |