SPAGNUOLO, ROSARIA
SPAGNUOLO, ROSARIA
FABIT - DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Dottorandi
Repurposing SGLT2 and DPP‐4 inhibitors for mild cognitive impairment in type 2 diabetes mellitus: Insights from proteomics, target prediction and molecular docking
2026 Osman, Shams T.; Elzahhar, Perihan A.; Hakim, Md Abdul; Sanni, Akeem; Hamdy, Noha A.; Purba, Waziha Tasnim; Bhuiyan, Md Mostofa Al Amin; Onigbinde, Sherifdeen; Sandilya, Vishal; Hassan, Nayera W.; Agami, Mahmoud; El‐khordagui, Labiba K.; Spagnuolo, Rosaria; Naldi, Marina; Bartolini, Manuela; Belal, Ahmed S. F.; Mechref, Yehia S.; El‐yazbi, Ahmed F.
Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of β-Amyloid and Tau Aggregation with Anticholinesterase Activity
2026 Verano, Aldrick B.; Sampietro, Anna; Mallo-Abreu, Ana; Spagnuolo, Rosaria; Pérez, Belén; Bartolini, Manuela; Loza, María Isabel; Brea, José; Juárez-Jiménez, Jordi; Sabate, Raimon; Galdeano, Carles; Muñoz-Torrero, Diego
Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease
2025 Orioli, R.; Sarno, G.; Seghetti, F.; Gobbi, S.; Belluti, F.; Feoli, A.; Massenzio, F.; Monti, B.; Spagnuolo, R.; Bartolini, M.; Castellano, S.; Bisi, A.
Multi-Target Glitazones for Modulating Peroxisome Proliferator-Activated Receptor-γ, Cyclooxygenase-2, and Carbonic Anhydrases for the Management of Metabolic Dysfunction
2025 Elzahhar, Perihan A.; Nematalla, Hisham A.; Abouayana, Malak A.; El Ashry, El Sayed H.; Balbaa, Mahmoud; Petreni, Andrea; Nassra, Rasha; Yassin, Hend A.; Kamel, Yasmine N.; Elrewiny, Mohamed A.; Agami, Mahmoud A.; Makkar, Monica; Sai, Minh; Merk, Daniel; Labib, Hala F.; Spagnuolo, Rosaria; Naldi, Marina; Bartolini, Manuela; El-Hawash, Soad A.; Supuran, Claudiu T.; Belal, Ahmed S. F.; El-Yazbi, Ahmed F.
Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies
2025 Di Martino, R. M. C.; Russo, D.; Penna, I.; Demuro, S.; Dalle Vedove, A.; Spagnuolo, R.; Ottonello, G.; Bertozzi, S. M.; Summa, M.; Desantis, J.; Valeri, A.; Pruccoli, L.; Tripathi, S. K.; Tarozzi, A.; Storici, P.; Girotto, S.; Bertorelli, R.; Armirotti, A.; Cruciani, G.; Bandiera, T.; Cavalli, A.; Bottegoni, G.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Repurposing SGLT2 and DPP‐4 inhibitors for mild cognitive impairment in type 2 diabetes mellitus: Insights from proteomics, target prediction and molecular docking | Osman, Shams T.; Elzahhar, Perihan A.; Hakim, Md Abdul; Sanni, Akeem; Hamdy, Noha A.; Purba, Wazi...ha Tasnim; Bhuiyan, Md Mostofa Al Amin; Onigbinde, Sherifdeen; Sandilya, Vishal; Hassan, Nayera W.; Agami, Mahmoud; El‐khordagui, Labiba K.; Spagnuolo, Rosaria; Naldi, Marina; Bartolini, Manuela; Belal, Ahmed S. F.; Mechref, Yehia S.; El‐yazbi, Ahmed F. | 2026-01-01 | BRITISH JOURNAL OF PHARMACOLOGY | - | 1.01 Articolo in rivista | - |
| Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of β-Amyloid and Tau Aggregation with Anticholinesterase Activity | Verano, Aldrick B.; Sampietro, Anna; Mallo-Abreu, Ana; Spagnuolo, Rosaria; Pérez, Belén; Bartolin...i, Manuela; Loza, María Isabel; Brea, José; Juárez-Jiménez, Jordi; Sabate, Raimon; Galdeano, Carles; Muñoz-Torrero, Diego | 2026-01-01 | BIOMOLECULES | - | 1.01 Articolo in rivista | - |
| Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease | Orioli, R.; Sarno, G.; Seghetti, F.; Gobbi, S.; Belluti, F.; Feoli, A.; Massenzio, F.; Monti, B.;... Spagnuolo, R.; Bartolini, M.; Castellano, S.; Bisi, A. | 2025-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | 1-s2.0-S0223523425005641-main.pdf |
| Multi-Target Glitazones for Modulating Peroxisome Proliferator-Activated Receptor-γ, Cyclooxygenase-2, and Carbonic Anhydrases for the Management of Metabolic Dysfunction | Elzahhar, Perihan A.; Nematalla, Hisham A.; Abouayana, Malak A.; El Ashry, El Sayed H.; Balbaa, M...ahmoud; Petreni, Andrea; Nassra, Rasha; Yassin, Hend A.; Kamel, Yasmine N.; Elrewiny, Mohamed A.; Agami, Mahmoud A.; Makkar, Monica; Sai, Minh; Merk, Daniel; Labib, Hala F.; Spagnuolo, Rosaria; Naldi, Marina; Bartolini, Manuela; El-Hawash, Soad A.; Supuran, Claudiu T.; Belal, Ahmed S. F.; El-Yazbi, Ahmed F. | 2025-01-01 | ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE | - | 1.01 Articolo in rivista | - |
| Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies | Di Martino, R. M. C.; Russo, D.; Penna, I.; Demuro, S.; Dalle Vedove, A.; Spagnuolo, R.; Ottonell...o, G.; Bertozzi, S. M.; Summa, M.; Desantis, J.; Valeri, A.; Pruccoli, L.; Tripathi, S. K.; Tarozzi, A.; Storici, P.; Girotto, S.; Bertorelli, R.; Armirotti, A.; Cruciani, G.; Bandiera, T.; Cavalli, A.; Bottegoni, G. | 2025-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | h_11585_1026573.pdf; ScienceDirect_files_05Nov2025_12-04-15.802.zip |