BRIGHENTI, ELISA
BRIGHENTI, ELISA
DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE (attivo dal 28/10/2011 al 31/12/2022)
The inhibition of lactate dehydrogenase A hinders the transcription of histone 2B gene independently from the block of aerobic glycolysis
2017 Brighenti, Elisa; Carnicelli, Domenica; Brigotti, Maurizio; Fiume, Luigi
Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate
2016 Scala, F.; Brighenti, E.; Govoni, M.; Imbrogno, E.; Fornari, F.; Treré, D.; Montanaro, L.; Derenzini, M
Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate
2016 Brighenti, Elisa; Giannone, Ferdinando Antonino; Fornari, Francesca; Onofrillo, Carmine; Govoni, Marzia; Montanaro, Lorenzo; Treré, Davide; Derenzini, Massimo
Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma
2015 Derenzini, Enrico; Agostinelli, Claudio; Imbrogno, Enrica; Iacobucci, Ilaria; Casadei, Beatrice; Brighenti, Elisa; Righi, Simona; Fuligni, Fabio; Ghelli Luserna Di Rorà, Andrea; Ferrari, Anna; Martinelli, Giovanni; Pileri, Stefano; Zinzani, Pier Luigi
Targeted cancer therapy with ribosome biogenesis inhibitors: A real possibility?
2015 Brighenti, Elisa; Treré, Davide; Derenzini, Massimo
Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer.
2014 Brighenti E;Calabrese C;Liguori G;Giannone FA;Trerè D;Montanaro L;Derenzini M
Inhibition of DNA repair by the small molecule Chk1/Chk2 inhibitor PF-0477736 (Pfizer) in B-acute lymphoblastic leukemia (ALL)
2012 Iacobucci I; Cattina F; Pomella S; Brighenti E; Papayannidis C; Derenzini E; Lonetti A; Ferrari A; Verga Falzacappa MV; Guadagnuolo V; Aluigi M; Ottaviani E; Abbenante MC; Soverini S; Russo D; Pelicci PG; Baccarani M; Martinelli G
Cell proliferation of esophageal squamous epithelium in erosive and non-erosive reflux disease
2011 C. Calabrese; L. Montanaro; G. Liguori; E. Brighenti; M. Vici; P. Gionchetti; F. Rizzello; M. Campieri; M. Derenzini; D. Trerè
Selective inhibition of rRNA transcription downregulates E2F-1: a new p53-independent mechanism linking cell growth to cell proliferation.
2011 Donati G; Brighenti E; Vici M; Mazzini G; Treré D; Montanaro L; Derenzini M.
The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells.
2011 Donati G; Bertoni S; Brighenti E; Vici M; Treré D; Volarevic S; Montanaro L; Derenzini M.
The Novel Small Molecule Chk1/Chk2 Inhibitor PF-0477736 (Pfizer) Is Highly Active As Single Agent in Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)
2011 Ilaria Iacobucci, Federica Cattina, Silvia Pomella, Annalisa Lonetti, Enrico Derenzini, Elisa Brighenti, Anna Ferrari, Cristina Papayannidis, Maria Vittoria Verga Falzacappa, Viviana Guadagnuolo, Michela Aluigi, Emanuela Ottaviani, Serena Formica, Maria Chiara Abbenante, Simona Soverini, Domenico Russo, Fabrizio Pane, Pier Guiseppe Pellicci, Michele Baccarani, Giovanni Martinelli
High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy.
2009 Treré D; Brighenti E; Donati G; Ceccarelli C; Santini D; Taffurelli M; Montanaro L; Derenzini M.
The p53-mediated sensitivity of cancer cells to chemotherapeutic agents is conditioned by the status of the retinoblastoma protein.
2009 Derenzini M; Brighenti E; Donati G; Vici M; Ceccarelli C; Santini D; Taffurelli M; Montanaro L; Treré D.
Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
2008 Tavolari S.; Bonafè M.; Marini M.; Ferreri C.; Bartolini G.; Brighenti E.; Manara S.; Tomasi V.; Laufer S.; Guarnieri T.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| The inhibition of lactate dehydrogenase A hinders the transcription of histone 2B gene independently from the block of aerobic glycolysis | Brighenti, Elisa; Carnicelli, Domenica; Brigotti, Maurizio; Fiume, Luigi | 2017-01-01 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - | 1.01 Articolo in rivista | - |
| Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate | Scala, F.; Brighenti, E.; Govoni, M.; Imbrogno, E.; Fornari, F.; Treré, D.; Montanaro, L.; Derenz...ini, M | 2016-01-01 | ONCOGENE | - | 1.01 Articolo in rivista | - |
| Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate | Brighenti, Elisa; Giannone, Ferdinando Antonino; Fornari, Francesca; Onofrillo, Carmine; Govoni, ...Marzia; Montanaro, Lorenzo; Treré, Davide; Derenzini, Massimo | 2016-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | Oncotarget2016Brighenti.pdf |
| Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma | Derenzini, Enrico; Agostinelli, Claudio; Imbrogno, Enrica; Iacobucci, Ilaria; Casadei, Beatrice; ...Brighenti, Elisa; Righi, Simona; Fuligni, Fabio; Ghelli Luserna Di Rorà, Andrea; Ferrari, Anna; Martinelli, Giovanni; Pileri, Stefano; Zinzani, Pier Luigi | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Targeted cancer therapy with ribosome biogenesis inhibitors: A real possibility? | Brighenti, Elisa; Treré, Davide; Derenzini, Massimo | 2015-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | 5775-78933-2-PB.pdf |
| Interleukin 6 downregulates p53 expression and activity by stimulating ribosome biogenesis: a new pathway connecting inflammation to cancer. | Brighenti E;Calabrese C;Liguori G;Giannone FA;Trerè D;Montanaro L;Derenzini M | 2014-01-01 | ONCOGENE | - | 1.01 Articolo in rivista | - |
| Inhibition of DNA repair by the small molecule Chk1/Chk2 inhibitor PF-0477736 (Pfizer) in B-acute lymphoblastic leukemia (ALL) | Iacobucci I; Cattina F; Pomella S; Brighenti E; Papayannidis C; Derenzini E; Lonetti A; Ferrari A...; Verga Falzacappa MV; Guadagnuolo V; Aluigi M; Ottaviani E; Abbenante MC; Soverini S; Russo D; Pelicci PG; Baccarani M; Martinelli G | 2012-01-01 | CANCER RESEARCH | - | 4.02 Riassunto (Abstract) | - |
| Cell proliferation of esophageal squamous epithelium in erosive and non-erosive reflux disease | C. Calabrese; L. Montanaro; G. Liguori; E. Brighenti; M. Vici; P. Gionchetti; F. Rizzello; M. Cam...pieri; M. Derenzini; D. Trerè | 2011-01-01 | WORLD JOURNAL OF GASTROENTEROLOGY | - | 1.01 Articolo in rivista | - |
| Selective inhibition of rRNA transcription downregulates E2F-1: a new p53-independent mechanism linking cell growth to cell proliferation. | Donati G; Brighenti E; Vici M; Mazzini G; Treré D; Montanaro L; Derenzini M. | 2011-01-01 | JOURNAL OF CELL SCIENCE | - | 1.01 Articolo in rivista | - |
| The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells. | Donati G; Bertoni S; Brighenti E; Vici M; Treré D; Volarevic S; Montanaro L; Derenzini M. | 2011-01-01 | ONCOGENE | - | 1.01 Articolo in rivista | - |
| The Novel Small Molecule Chk1/Chk2 Inhibitor PF-0477736 (Pfizer) Is Highly Active As Single Agent in Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) | Ilaria Iacobucci, Federica Cattina, Silvia Pomella, Annalisa Lonetti, Enrico Derenzini, Elisa Bri...ghenti, Anna Ferrari, Cristina Papayannidis, Maria Vittoria Verga Falzacappa, Viviana Guadagnuolo, Michela Aluigi, Emanuela Ottaviani, Serena Formica, Maria Chiara Abbenante, Simona Soverini, Domenico Russo, Fabrizio Pane, Pier Guiseppe Pellicci, Michele Baccarani, Giovanni Martinelli | 2011-01-01 | BLOOD | - | 1.06 Abstract in rivista | - |
| High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy. | Treré D; Brighenti E; Donati G; Ceccarelli C; Santini D; Taffurelli M; Montanaro L; Derenzini M. | 2009-01-01 | ANNALS OF ONCOLOGY | - | 1.01 Articolo in rivista | - |
| The p53-mediated sensitivity of cancer cells to chemotherapeutic agents is conditioned by the status of the retinoblastoma protein. | Derenzini M; Brighenti E; Donati G; Vici M; Ceccarelli C; Santini D; Taffurelli M; Montanaro L; T...reré D. | 2009-01-01 | JOURNAL OF PATHOLOGY | - | 1.01 Articolo in rivista | - |
| Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. | Tavolari S.; Bonafè M.; Marini M.; Ferreri C.; Bartolini G.; Brighenti E.; Manara S.; Tomasi V.; ...Laufer S.; Guarnieri T. | 2008-01-01 | CARCINOGENESIS | - | 1.01 Articolo in rivista | - |