MANCINI, FRANCESCA
MANCINI, FRANCESCA
DIP. DI SCIENZE FARMACEUTICHE
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment
2016 Rampa, Angela; Tarozzi, Andrea; Mancini, Francesca; Pruccoli, Letizia; Di Martino, Rita Maria Concetta; Gobbi, Silvia; Bisi, Alessandra; De Simone, Angela; Palomba, Francesco; Zaccheroni, Nelsi; Belluti, Federica
Human recombinant beta-secretase immobilized enzyme reactor for fast hits’ selection and characterization from a virtual screening library
2013 Angela De Simone;Francesca Mancini;Sandro Cosconati;Luciana Marinelli;Valeria La Pietra;Ettore Novellino;Vincenza Andrisano
Surface plasmon resonance, fluorescence, and circular dichroism studies for the characterization of the binding of BACE-1 inhibitors
2013 Angela De Simone;Francesca Mancini;Feliciana Real Fernàndez;Paolo Rovero;Carlo Bertucci;Vincenza Andrisano
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation
2012 G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A. Martinez; V. Andrisano; P. Carloni; M. Roberti
An immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER) for the fast processing of substrates and screening of inhibitors
2012 Chlebek, Jakub; De Simone, Angela; Mancini, Francesca; Andrisano, Vincenza
Curcumin derivatives as beta-secretase (BACE1) inhibitors.
2012 De Simone, A; Mancini, F; Belluti, F; Bartolini, M; Bottegoni, G.; Rampa, A.; Cavalli, A.; Andrisano, V.
Protein Flexibility in Virtual Screening: The BACE-1 Case Study
2012 Cosconati S.; Marinelli L.; Di Leva F.S.; La Pietra V.; De Simone A.; Mancini F.; Andrisano V.; Novellino E.; Goodsell D.S.; Olson A.J.
Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors.
2011 F. Mancini; A. De Simone; V. Andrisano
Sequential Virtual Screening Approach to the Identification of Small Organic Molecules as Potential BACE-1 Inhibitors
2011 Chiriano G.; Sartini A.; Mancini F.; Andrisano V.; Bolognesi M. L.; Roberti M.; Recanatini M.; Carloni P.; Cavalli A.
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions
2011 Bolognesi ML; Chiriano G; Bartolini M; Mancini F; Bottegoni G; Maestri V; Czvitkovich S; Windisch M; Cavalli A; Minarini A; Rosini M; Tumiatti V; Andrisano V; Melchiorre C.
A multi-approach study for BACE-1 inhibitors characterization.
2010 Angela De Simone; F. Mancini; C. Bertucci; V. Andrisano
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities
2010 Bolognesi ML; Bartolini M ; Mancini F ; Chiriano G ; Ceccarini L; Rosini M; Milelli A; Tumiatti V; Andrisano V; Melchiorre C
Development of a liquid chromatographic system with fluorescent detection for beta-secretase immobilized enzyme reactor on-line enzymatic studies
2010 F. Mancini; V. Andrisano
Micro-immobilized enzyme reactor based on human recombinant beta secretase (hrBACE-1-microIMER) for liquid chromatography fast screening of inhibitors.
2010 De Simone, A.; Mancini, F.; Andrisano, V.
Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-alzheimer drug candidates
2010 E. Viayna; T. Gómez; C. Galdeano; L. Ramírez; M. Ratia ; A. Badia; M.V. Clos; E. Verdaguer; F. Junyent; A. Camins; M. Pallàs; M. Bartolini; F. Mancini; V. Andrisano; M.P. Arce; M.I. Rodríguez-Franco; A. Bidon-Chanal; F.J. Luque; P. Camps; D. Muñoz-Torrero
Surface plasmon resonance assay for BACE-1 inhibitors’ characterization.
2010 De Simone, A.; Real, F.; Mancini, F.; Rovero, P.; Andrisano, V.; Bertucci, C.
Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates
2010 P. Camps; X. Formosa; C. Galdeano; T. Gómez; D. Muñoz-Torrero; L. Ramírez; E. Viayna; E. Gómez; N. Isambert; R. Lavilla; A. Badia; M.V. Clos; M. Bartolini; F. Mancini; V. Andrisano; A. Bidon-Chanal; O. Huertas; T. Dafni; F.J. Luque
ALZHEIMER'S DISEASE DRUG DISCOVERY: NEW ANALYTICAL APPROACHES FOR LEAD SELECTION AND OPTIMIZATION PBA 2009 (20h International Symposium on Pharmaceutical and Biomedical Analysis), Agra, India 01-04 Marzo 2009
2009 V.Andrisano; M.Bartolini; F.Mancini; M.Naldi
APPLICATION OF AN IMMOBILIZED ENZYME REACTOR BASED ON HUMAN RECOMBINANT BETA-SECRETASE (HRBACE-1-IMER) FOR THE FAST SCREENING OF INHIBITORS
2009 F. Mancini; V. Andrisano
HUPRINETACRINE HYBRIDS AS A NOVEL FAMILY OF MULTI-TARGET DRUG CANDIDATES AGAINST ALZHEIMER’S AND PRION DISEASES
2009 D. Muñoz-Torrero; P. Camps; X. Formosa; C. Galdeano; E. Viayna; A. Badia; M. Victòria Clos; M. Pera; M. Ratia; B. Pérez Fernández; M. Bartolini; F. Mancini; V. Andrisano; G. C. González-Muñoz; M. I. Rodríguez-Franco; L. Rivail; F. J. Luque
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment | Rampa, Angela; Tarozzi, Andrea; Mancini, Francesca; Pruccoli, Letizia; Di Martino, Rita Maria Con...cetta; Gobbi, Silvia; Bisi, Alessandra; De Simone, Angela; Palomba, Francesco; Zaccheroni, Nelsi; Belluti, Federica | 2016-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-21-00643.pdf |
| Human recombinant beta-secretase immobilized enzyme reactor for fast hits’ selection and characterization from a virtual screening library | Angela De Simone;Francesca Mancini;Sandro Cosconati;Luciana Marinelli;Valeria La Pietra;Ettore No...vellino;Vincenza Andrisano | 2013-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Surface plasmon resonance, fluorescence, and circular dichroism studies for the characterization of the binding of BACE-1 inhibitors | Angela De Simone;Francesca Mancini;Feliciana Real Fernàndez;Paolo Rovero;Carlo Bertucci;Vincenza ...Andrisano | 2013-01-01 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation | G. P. Chiriano; A. De Simone; F. Mancini; D. I. Perez; A. Cavalli; M. L. Bolognesi; G. Legname; A.... Martinez; V. Andrisano; P. Carloni; M. Roberti | 2012-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| An immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER) for the fast processing of substrates and screening of inhibitors | Chlebek, Jakub; De Simone, Angela; Mancini, Francesca; Andrisano, Vincenza | 2012-01-01 | - | - | 4.03 Poster | - |
| Curcumin derivatives as beta-secretase (BACE1) inhibitors. | De Simone, A; Mancini, F; Belluti, F; Bartolini, M; Bottegoni, G.; Rampa, A.; Cavalli, A.; Andris...ano, V. | 2012-01-01 | - | - | 4.03 Poster | - |
| Protein Flexibility in Virtual Screening: The BACE-1 Case Study | Cosconati S.; Marinelli L.; Di Leva F.S.; La Pietra V.; De Simone A.; Mancini F.; Andrisano V.; N...ovellino E.; Goodsell D.S.; Olson A.J. | 2012-01-01 | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - | 1.01 Articolo in rivista | - |
| Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors. | F. Mancini; A. De Simone; V. Andrisano | 2011-01-01 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Sequential Virtual Screening Approach to the Identification of Small Organic Molecules as Potential BACE-1 Inhibitors | Chiriano G.; Sartini A.; Mancini F.; Andrisano V.; Bolognesi M. L.; Roberti M.; Recanatini M.; Ca...rloni P.; Cavalli A. | 2011-01-01 | CHEMICAL BIOLOGY & DRUG DESIGN | - | 1.01 Articolo in rivista | - |
| Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions | Bolognesi ML; Chiriano G; Bartolini M; Mancini F; Bottegoni G; Maestri V; Czvitkovich S; Windisch... M; Cavalli A; Minarini A; Rosini M; Tumiatti V; Andrisano V; Melchiorre C. | 2011-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| A multi-approach study for BACE-1 inhibitors characterization. | Angela De Simone; F. Mancini; C. Bertucci; V. Andrisano | 2010-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities | Bolognesi ML; Bartolini M ; Mancini F ; Chiriano G ; Ceccarini L; Rosini M; Milelli A; Tumiatti V...; Andrisano V; Melchiorre C | 2010-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Development of a liquid chromatographic system with fluorescent detection for beta-secretase immobilized enzyme reactor on-line enzymatic studies | F. Mancini; V. Andrisano | 2010-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Micro-immobilized enzyme reactor based on human recombinant beta secretase (hrBACE-1-microIMER) for liquid chromatography fast screening of inhibitors. | De Simone, A.; Mancini, F.; Andrisano, V. | 2010-01-01 | - | - | 4.03 Poster | - |
| Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-alzheimer drug candidates | E. Viayna; T. Gómez; C. Galdeano; L. Ramírez; M. Ratia ; A. Badia; M.V. Clos; E. Verdaguer; F. Ju...nyent; A. Camins; M. Pallàs; M. Bartolini; F. Mancini; V. Andrisano; M.P. Arce; M.I. Rodríguez-Franco; A. Bidon-Chanal; F.J. Luque; P. Camps; D. Muñoz-Torrero | 2010-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Surface plasmon resonance assay for BACE-1 inhibitors’ characterization. | De Simone, A.; Real, F.; Mancini, F.; Rovero, P.; Andrisano, V.; Bertucci, C. | 2010-01-01 | - | - | 4.03 Poster | - |
| Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates | P. Camps; X. Formosa; C. Galdeano; T. Gómez; D. Muñoz-Torrero; L. Ramírez; E. Viayna; E. Gómez; N.... Isambert; R. Lavilla; A. Badia; M.V. Clos; M. Bartolini; F. Mancini; V. Andrisano; A. Bidon-Chanal; O. Huertas; T. Dafni; F.J. Luque | 2010-01-01 | CHEMICO-BIOLOGICAL INTERACTIONS | - | 1.01 Articolo in rivista | - |
| ALZHEIMER'S DISEASE DRUG DISCOVERY: NEW ANALYTICAL APPROACHES FOR LEAD SELECTION AND OPTIMIZATION PBA 2009 (20h International Symposium on Pharmaceutical and Biomedical Analysis), Agra, India 01-04 Marzo 2009 | V.Andrisano; M.Bartolini; F.Mancini; M.Naldi | 2009-01-01 | - | s.n | 4.01 Contributo in Atti di convegno | - |
| APPLICATION OF AN IMMOBILIZED ENZYME REACTOR BASED ON HUMAN RECOMBINANT BETA-SECRETASE (HRBACE-1-IMER) FOR THE FAST SCREENING OF INHIBITORS | F. Mancini; V. Andrisano | 2009-01-01 | - | s.n | 4.01 Contributo in Atti di convegno | - |
| HUPRINETACRINE HYBRIDS AS A NOVEL FAMILY OF MULTI-TARGET DRUG CANDIDATES AGAINST ALZHEIMER’S AND PRION DISEASES | D. Muñoz-Torrero; P. Camps; X. Formosa; C. Galdeano; E. Viayna; A. Badia; M. Victòria Clos; M. Pe...ra; M. Ratia; B. Pérez Fernández; M. Bartolini; F. Mancini; V. Andrisano; G. C. González-Muñoz; M. I. Rodríguez-Franco; L. Rivail; F. J. Luque | 2009-01-01 | - | ZRINKA KOVARIK | 4.01 Contributo in Atti di convegno | - |