DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Personale esterno ed autonomi
A long antisense RNA is transcribed at the 5’ end of the human HIF-1a gene upon drug inhibition of DNA Topoisomerase I.
2008-01-01 Baranello L.; Bertozzi D.; Capranico G.
Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity.
2010-01-01 G. Capranico; J. Marinello; L. Baranello
DNA topoisomerase I (Top1) can regulate the coupling of RNA polymerase II (RNAP) pausing at promoter-proximal sites and transcript maturation in human cells.
2007-01-01 Fogli M.V.; Baranello L.; Ferri F.; Pommier Y.; Capranico G.
DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1a gene locus.
2010-01-01 L. Baranello; D. Bertozzi; M.V. Fogli; Y. Pommier; G. Capranico
Induction of a novel long antisense RNA from the human HIF-1a locus may contribuite to HIF 1a regulation and inhibition by campotecin in cancer cells.
2009-01-01 Baranello L; Bertozzi D; Pommier Y; Capranico G.
The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I.
2007-01-01 Capranico G.; Ferri F.; Fogli M.V.; Russo A.; Lotito L.; Baranello L.
Topoisomerase I specifically affects RNA polymerase II paused at promoter-proximal sites in human cells.
2006-01-01 F. Ferri; L. Baranello; A. Khobta; O. Sordet; M. Zhehong; Y. Pommier; G. Capranico