The purpose of the present study was to make a histological analysis of the remodelling process of hamstring tendon graft used as Anterior Cruciate Ligament (ACL). The hamstring graft of eight patients was biopsied at different follow-up times from 1 to 10 years. The specimens were analysed with transmission electron microscopy (TEM) at ultrastructural level comparing them with a native ACL and a native hamstring graft. The hamstring graft was found to undergo ultrastructural changes in terms of number and diameter of fibrils with the major changes occurring in the first 2 years. At longer times after surgery (48 and 120 months) no important further changes were evident and the ultrastructure did not vary substantially from 2 to 10 years. In conclusion, the hamstring tendon used as ACL graft undergoes a transformation process but does not match the ultrastructure pattern of a normal ACL up to 10 years.

Electron microscopy of the remodelling process in hamstring tendon used as ACL graft / Zaffagnini S.; De Pasquale V.; Marchesini Reggiani L.; Russo A.; Agati P.; Bacchelli B.; Marcacci M.. - In: KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY. - ISSN 0942-2056. - STAMPA. - 18 (8):(2010), pp. 1052-1058. [10.1007/s00167-009-0925-7]

Electron microscopy of the remodelling process in hamstring tendon used as ACL graft

ZAFFAGNINI, STEFANO;DE PASQUALE, VIVIANA;MARCHESINI REGGIANI, LEONARDO;AGATI, PATRIZIA;BACCHELLI, BEATRICE;MARCACCI, MAURILIO
2010

Abstract

The purpose of the present study was to make a histological analysis of the remodelling process of hamstring tendon graft used as Anterior Cruciate Ligament (ACL). The hamstring graft of eight patients was biopsied at different follow-up times from 1 to 10 years. The specimens were analysed with transmission electron microscopy (TEM) at ultrastructural level comparing them with a native ACL and a native hamstring graft. The hamstring graft was found to undergo ultrastructural changes in terms of number and diameter of fibrils with the major changes occurring in the first 2 years. At longer times after surgery (48 and 120 months) no important further changes were evident and the ultrastructure did not vary substantially from 2 to 10 years. In conclusion, the hamstring tendon used as ACL graft undergoes a transformation process but does not match the ultrastructure pattern of a normal ACL up to 10 years.
2010
Electron microscopy of the remodelling process in hamstring tendon used as ACL graft / Zaffagnini S.; De Pasquale V.; Marchesini Reggiani L.; Russo A.; Agati P.; Bacchelli B.; Marcacci M.. - In: KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY. - ISSN 0942-2056. - STAMPA. - 18 (8):(2010), pp. 1052-1058. [10.1007/s00167-009-0925-7]
Zaffagnini S.; De Pasquale V.; Marchesini Reggiani L.; Russo A.; Agati P.; Bacchelli B.; Marcacci M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/98069
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