Two original methods were developed and compared for TDM of topiramate: one based on HPLC with fluorescence detection and one based on CE with indirect UV detectio. Both analytical methods, fully validated, have shown to be suitable for the monitoring of patients undergoing therapy with topiramate.
Comparison of CE and HPLC for the Therapeutic Drug Monitoring of the Antiepileptic Drug Topiramate.
MANDRIOLI, ROBERTO;MERCOLINI, LAURA;GHEDINI, NADIA;RAGGI, MARIA AUGUSTA
2010
Abstract
Two original methods were developed and compared for TDM of topiramate: one based on HPLC with fluorescence detection and one based on CE with indirect UV detectio. Both analytical methods, fully validated, have shown to be suitable for the monitoring of patients undergoing therapy with topiramate.File in questo prodotto:
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