Natural solutions: The instinctive desire of organic chemists to imitate the catalytic machinery of enzymes has brought about the development of the first catalytic highly enantioselective synthesis of α-amino acid derivatives by biomimetic transamination. Key to success was the ability of a cinchona-based chiral catalyst to mimic the general base–acid catalytic mechanism of the natural transaminases.
A Bio-Inspired Route to α-Amino Acid Derivatives / Arceo E.; Melchiorre P.. - In: CHEMCATCHEM. - ISSN 1867-3880. - ELETTRONICO. - 4:4(2012), pp. 459-461. [10.1002/cctc.201100394]
A Bio-Inspired Route to α-Amino Acid Derivatives
Melchiorre P.
Ultimo
Supervision
2012
Abstract
Natural solutions: The instinctive desire of organic chemists to imitate the catalytic machinery of enzymes has brought about the development of the first catalytic highly enantioselective synthesis of α-amino acid derivatives by biomimetic transamination. Key to success was the ability of a cinchona-based chiral catalyst to mimic the general base–acid catalytic mechanism of the natural transaminases.File in questo prodotto:
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