Efficient methodologies based on consecutive radical ractions for the preparation of cyclonucleosides are reported. The reactions were performed on modified thymidine and 2'-deoxyadenosine substrates using (TMS)3SiH as the reducing agent. The rate constants for the 6-exo-trig radical cyclization have been estimated.

Radical cyclization approach to cyclonucleosides

MONTEVECCHI, PIER CARLO;
2005

Abstract

Efficient methodologies based on consecutive radical ractions for the preparation of cyclonucleosides are reported. The reactions were performed on modified thymidine and 2'-deoxyadenosine substrates using (TMS)3SiH as the reducing agent. The rate constants for the 6-exo-trig radical cyclization have been estimated.
2005
L. Navacchia; A. Manetto; P. C. Montevecchi; C. Chatgilialoglu
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/8972
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