Several studies highlighted a correlation between folic acid deficiency and high plasma homocysteine concentration, considered a risk factor for multifactorial diseases. Natural folates represent an emerging alternative strategy to supplementation with synthetic folic acid, whose effects are controversial. The present work was, therefore, performed in hyperhomocysteinemic mice to study the impact of supplementation with dairy matrices containing natural folates on plasma homocysteine levels and faecal microbiota composition.
Supplementation with dairy matrices impacts on homocysteine levels and gut microbiota composition of hyperhomocysteinemic mice / Zinno, Paola; Motta, Vincenzo; Guantario, Barbara; Natella, Fausta; Roselli, Marianna; Bello, Cristiano; Comitato, Raffaella; Carminati, Domenico; Tidona, Flavio; Meucci, Aurora; Aiello, Paola; Perozzi, Giuditta; Virgili, Fabio; Trevisi, Paolo; Canali, Raffaella; Devirgiliis, Chiara. - In: EUROPEAN JOURNAL OF NUTRITION. - ISSN 1436-6215. - ELETTRONICO. - 59:(2020), pp. 345-358. [10.1007/s00394-019-01911-y]
Supplementation with dairy matrices impacts on homocysteine levels and gut microbiota composition of hyperhomocysteinemic mice
Motta, VincenzoSecondo
Writing – Original Draft Preparation
;Trevisi, PaoloSupervision
;
2020
Abstract
Several studies highlighted a correlation between folic acid deficiency and high plasma homocysteine concentration, considered a risk factor for multifactorial diseases. Natural folates represent an emerging alternative strategy to supplementation with synthetic folic acid, whose effects are controversial. The present work was, therefore, performed in hyperhomocysteinemic mice to study the impact of supplementation with dairy matrices containing natural folates on plasma homocysteine levels and faecal microbiota composition.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
