Introduction: Granular cellular tumors are unusual lesions that can occur in the gastrointestinal tract, where they localize most commonly to the esophagus followed by the colon. Areas covered: We report a case of a young man with a sub-epithelial lesion of the ascending colon, removed by endoscopic submucosal dissection. Histological examination revealed a granular cellular tumor without features of malignancy. We present a systematic review of the English literature evaluating granular cellular tumors of lower gastrointestinal tract. Expert commentary: These tumors are usually asymptomatic and discovered incidentally during endoscopy performed for other reasons. Though their histological behavior is usually benign, 1-2% are malignant. Therefore, it is important that these lesions are excised and adequately pathologically characterized.

Granular Data: A Rare Submucosal Tumor of the Colon-Case Report and Review of the Literature

Pagano, Nico;Impellizzeri, Giovanna;Di Simone, Massimo P;Rottoli, Matteo
;
Poggioli, Gilberto
2021

Abstract

Introduction: Granular cellular tumors are unusual lesions that can occur in the gastrointestinal tract, where they localize most commonly to the esophagus followed by the colon. Areas covered: We report a case of a young man with a sub-epithelial lesion of the ascending colon, removed by endoscopic submucosal dissection. Histological examination revealed a granular cellular tumor without features of malignancy. We present a systematic review of the English literature evaluating granular cellular tumors of lower gastrointestinal tract. Expert commentary: These tumors are usually asymptomatic and discovered incidentally during endoscopy performed for other reasons. Though their histological behavior is usually benign, 1-2% are malignant. Therefore, it is important that these lesions are excised and adequately pathologically characterized.
2021
Pagano, Nico; Impellizzeri, Giovanna; Di Simone, Massimo P; Rottoli, Matteo; Pirini, Maria G; Lauro, Augusto; Pallio, Socrate; Poggioli, Gilberto
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/788534
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