Introduction: Granular cellular tumors are unusual lesions that can occur in the gastrointestinal tract, where they localize most commonly to the esophagus followed by the colon. Areas covered: We report a case of a young man with a sub-epithelial lesion of the ascending colon, removed by endoscopic submucosal dissection. Histological examination revealed a granular cellular tumor without features of malignancy. We present a systematic review of the English literature evaluating granular cellular tumors of lower gastrointestinal tract. Expert commentary: These tumors are usually asymptomatic and discovered incidentally during endoscopy performed for other reasons. Though their histological behavior is usually benign, 1-2% are malignant. Therefore, it is important that these lesions are excised and adequately pathologically characterized.
Titolo: | Granular Data: A Rare Submucosal Tumor of the Colon-Case Report and Review of the Literature |
Autore/i: | Pagano, Nico; Impellizzeri, Giovanna; Di Simone, Massimo P; Rottoli, Matteo; Pirini, Maria G; Lauro, Augusto; Pallio, Socrate; Poggioli, Gilberto |
Autore/i Unibo: | |
Anno: | 2021 |
Rivista: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s10620-020-06753-x |
Abstract: | Introduction: Granular cellular tumors are unusual lesions that can occur in the gastrointestinal tract, where they localize most commonly to the esophagus followed by the colon. Areas covered: We report a case of a young man with a sub-epithelial lesion of the ascending colon, removed by endoscopic submucosal dissection. Histological examination revealed a granular cellular tumor without features of malignancy. We present a systematic review of the English literature evaluating granular cellular tumors of lower gastrointestinal tract. Expert commentary: These tumors are usually asymptomatic and discovered incidentally during endoscopy performed for other reasons. Though their histological behavior is usually benign, 1-2% are malignant. Therefore, it is important that these lesions are excised and adequately pathologically characterized. |
Data stato definitivo: | 2021-01-13T15:51:44Z |
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