Although far less common now than in the past, syphilis continues to pose a danger to public health and should not be overlooked. In this study, we evaluated the presence and characteristics of syphilis in a group of patients attending an STI Clinic in the North of Italy. A retrospective study was carried out, analysing the data from the 5609 subjects who attended the STI Clinic of St. Orsola-Malpighi Hospital (Bologna) for syphilis screening from January 2016 to December 2017. Globally, 692 patients (12.3%) were found positive for treponemal tests, with a significant difference between males and females (16.6% vs 4.1%; P<0.0001). Moreover, positive women were more likely foreign (63.3%), in contrast to men, who were more likely Italian (86.1%; P<0.0001). A total of 306 patients (44.2%), mainly males (47% vs 25%; P=0.0003), received a diagnosis of early syphilis. These cases peaked among patients 35-44 years (31%) and 25-34 years (26.8%). Overall, 32.9% of the women found positive for treponemal tests were pregnant. Among them, 84.6% were foreign (mainly from Eastern Europe) and 38.4% received a diagnosis of early syphilis. No cases of mother-to-child syphilis were found. The presence of an HIV-syphilis co-infection was found in 21.5% of patients with early syphilis, with a significant association with the male sex (P<0.009). In-depth knowledge of the characteristics of syphilis could help set up effective strategies for its control.

Syphilis in a high-density urban area in the North of Italy / Roncarati, Greta; Fazio, Chiara; Gaspari, Valeria; Marziali, Giacomo; Furlini, Giuliano; Galli, Silvia; Moroni, Alessandra; Foschi, Claudio; Marangoni, Antonella; D'Antuono, Antonietta. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - ELETTRONICO. - 42:3(2019), pp. 166-170.

Syphilis in a high-density urban area in the North of Italy

Roncarati, Greta;Fazio, Chiara;GASPARI, VALERIA;Marziali, Giacomo;Furlini, Giuliano;Foschi, Claudio;Marangoni, Antonella;D'Antuono, Antonietta
2019

Abstract

Although far less common now than in the past, syphilis continues to pose a danger to public health and should not be overlooked. In this study, we evaluated the presence and characteristics of syphilis in a group of patients attending an STI Clinic in the North of Italy. A retrospective study was carried out, analysing the data from the 5609 subjects who attended the STI Clinic of St. Orsola-Malpighi Hospital (Bologna) for syphilis screening from January 2016 to December 2017. Globally, 692 patients (12.3%) were found positive for treponemal tests, with a significant difference between males and females (16.6% vs 4.1%; P<0.0001). Moreover, positive women were more likely foreign (63.3%), in contrast to men, who were more likely Italian (86.1%; P<0.0001). A total of 306 patients (44.2%), mainly males (47% vs 25%; P=0.0003), received a diagnosis of early syphilis. These cases peaked among patients 35-44 years (31%) and 25-34 years (26.8%). Overall, 32.9% of the women found positive for treponemal tests were pregnant. Among them, 84.6% were foreign (mainly from Eastern Europe) and 38.4% received a diagnosis of early syphilis. No cases of mother-to-child syphilis were found. The presence of an HIV-syphilis co-infection was found in 21.5% of patients with early syphilis, with a significant association with the male sex (P<0.009). In-depth knowledge of the characteristics of syphilis could help set up effective strategies for its control.
2019
Syphilis in a high-density urban area in the North of Italy / Roncarati, Greta; Fazio, Chiara; Gaspari, Valeria; Marziali, Giacomo; Furlini, Giuliano; Galli, Silvia; Moroni, Alessandra; Foschi, Claudio; Marangoni, Antonella; D'Antuono, Antonietta. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - ELETTRONICO. - 42:3(2019), pp. 166-170.
Roncarati, Greta; Fazio, Chiara; Gaspari, Valeria; Marziali, Giacomo; Furlini, Giuliano; Galli, Silvia; Moroni, Alessandra; Foschi, Claudio; Marangoni, Antonella; D'Antuono, Antonietta
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/696745
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