A disposable acetaminophen biosensor based on inkjet‐printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet‐printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility.

Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications / Stanković, Dalibor M.; Ognjanović, Miloš; Jović, Milica; Cuplić, Valentina; Lesch, Andreas; Girault, Hubert H.; Gavrović Jankulović, Marija; Antić, Bratislav. - In: ELECTROANALYSIS. - ISSN 1040-0397. - ELETTRONICO. - 31:(2019), pp. 1517-1525. [10.1002/elan.201900129]

Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications

Lesch, Andreas;
2019

Abstract

A disposable acetaminophen biosensor based on inkjet‐printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet‐printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility.
2019
Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet‐printed CNT Electrodes‐droplet Based Paracetamol Detection in Biological Fluids for “Point‐of‐care” Applications / Stanković, Dalibor M.; Ognjanović, Miloš; Jović, Milica; Cuplić, Valentina; Lesch, Andreas; Girault, Hubert H.; Gavrović Jankulović, Marija; Antić, Bratislav. - In: ELECTROANALYSIS. - ISSN 1040-0397. - ELETTRONICO. - 31:(2019), pp. 1517-1525. [10.1002/elan.201900129]
Stanković, Dalibor M.; Ognjanović, Miloš; Jović, Milica; Cuplić, Valentina; Lesch, Andreas; Girault, Hubert H.; Gavrović Jankulović, Marija; Antić, Bratislav
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/695132
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