Low temperature NMR spectra show that the title compound exist as a pair of conformational enantiomers, generated by the restricted rotation about the C9-Pri bond, the corresponding interconversion barrier being 6.9 kcal mol-1. This interpretation is supported by theoretical (MM and DFT) calculations and by the experimental determination of the analogous barriers occurring in the related MeC=O and ButC=O derivatives.
Stereomutation of Conformational Enantiomers of 9-Isopropyl-9-formyl fluorene and Related Acyl Derivatives / D. Casarini; L. Lunazzi; A. Mazzanti. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - STAMPA. - 73:(2008), pp. 6382-6385. [10.1021/jo8008897]
Stereomutation of Conformational Enantiomers of 9-Isopropyl-9-formyl fluorene and Related Acyl Derivatives
LUNAZZI, LODOVICO;MAZZANTI, ANDREA
2008
Abstract
Low temperature NMR spectra show that the title compound exist as a pair of conformational enantiomers, generated by the restricted rotation about the C9-Pri bond, the corresponding interconversion barrier being 6.9 kcal mol-1. This interpretation is supported by theoretical (MM and DFT) calculations and by the experimental determination of the analogous barriers occurring in the related MeC=O and ButC=O derivatives.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
