Histological regression in primary cutaneous melanoma occurs in 10-35% of cases. Although there is a large body of literature on histological regression and prognosis in melanoma patients, not clear data concerning this feature has been reported. In the current review, a comprehensive overview of the main aspects of regression will be provided. The clinical utility of regression as a prognostic factor has been challenged recently. Nowadays evidences reported that this feature is protective on SLN metastases. Despite its association with poor prognostic factors, it maintained a favourable prognostic role in many different survival studies.
Prognostic role of histological regression in cutaneous melanoma / Ribero, Simone; Osella-Abate, Simona; Dika, Emi; Baduel, Eugenio Sportoletti; Marra, Elena; Picciotto, Franco; Caliendo, Virginia; Fierro, Maria T.; Quaglino, Pietro. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 0392-0488. - STAMPA. - 152:6(2017), pp. 638-641. [10.23736/S0392-0488.16.05442-0]
Prognostic role of histological regression in cutaneous melanoma
Dika, Emi;
2017
Abstract
Histological regression in primary cutaneous melanoma occurs in 10-35% of cases. Although there is a large body of literature on histological regression and prognosis in melanoma patients, not clear data concerning this feature has been reported. In the current review, a comprehensive overview of the main aspects of regression will be provided. The clinical utility of regression as a prognostic factor has been challenged recently. Nowadays evidences reported that this feature is protective on SLN metastases. Despite its association with poor prognostic factors, it maintained a favourable prognostic role in many different survival studies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
