Background Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinsonâs disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. Objectives To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. Methods This article reports data of patientsâ perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relationship between well-being and clinical characteristics including fatigue, depression, sleep disruption and HRQoL. Results 272 patients completed the PWS questionnaire. Significant and clinically-relevant correlations were found between PWS total score and Parkinsonâs Fatigue Scale, Beck Depression Inventory, UPDRS Section I, PD Sleep Scale and PDQ-39 for HRQoL scores. Only clinically negligible correlations were found between PWS and motor scores. Conclusions Non-motor symptoms have a significant impact on psychological well-being in PD patients.
Factors influencing psychological well-being in patients with Parkinsonâ s disease / Nicoletti, Alessandra; Mostile, Giovanni; Stocchi, Fabrizio; Abbruzzese, Giovanni; Ceravolo, Roberto; Cortelli, Pietro; Dâ amelio, Marco; De Pandis, Maria F.; Fabbrini, Giovanni; Pacchetti, Claudio; Pezzoli, Gianni; Tessitore, Alessandro; Canesi, Margherita; Zappia, Mario. - In: PLOS ONE. - ISSN 1932-6203. - ELETTRONICO. - 12:12(2017), pp. e0189682.e0189682-e0189682.e0189682. [10.1371/journal.pone.0189682]
Factors influencing psychological well-being in patients with Parkinsonâs disease
Cortelli, Pietro;
2017
Abstract
Background Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinsonâs disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. Objectives To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. Methods This article reports data of patientsâ perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relationship between well-being and clinical characteristics including fatigue, depression, sleep disruption and HRQoL. Results 272 patients completed the PWS questionnaire. Significant and clinically-relevant correlations were found between PWS total score and Parkinsonâs Fatigue Scale, Beck Depression Inventory, UPDRS Section I, PD Sleep Scale and PDQ-39 for HRQoL scores. Only clinically negligible correlations were found between PWS and motor scores. Conclusions Non-motor symptoms have a significant impact on psychological well-being in PD patients.File | Dimensione | Formato | |
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