Imidazo[2,1-b]thiazole is a fused heterobicyclic system containing bridgehead nitrogen atom. Derivatives of this scaffold are especially attractive in the field of medicinal chemistry because of their broad spectrum of biological activities. The imidazo[2,1-b]thiazole system constitutes the core unit of the well-known anthelminthic and immunomodulatory agent Levamisole, marketed under the trade name Ergamisol© and discovered at Janssen Pharmaceutica in 1966.

Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective

LEONI, ALBERTO;LOCATELLI, ALESSANDRA;MORIGI, RITA;RAMBALDI, MIRELLA
2017

Abstract

Imidazo[2,1-b]thiazole is a fused heterobicyclic system containing bridgehead nitrogen atom. Derivatives of this scaffold are especially attractive in the field of medicinal chemistry because of their broad spectrum of biological activities. The imidazo[2,1-b]thiazole system constitutes the core unit of the well-known anthelminthic and immunomodulatory agent Levamisole, marketed under the trade name Ergamisol© and discovered at Janssen Pharmaceutica in 1966.
2017
Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/607066
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