The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. In the context of hepatological practice, however, ALF refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. The disease process is associated with development of a coagulopathy of liver aetiology, and clinically apparent altered level of consciousness due to hepatic encephalopathy. Several important measures are immediately necessary when the patient presents for medical attention. These, as well as additional clinical procedures will be the subject of these clinical practice guidelines.
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure / Wendon J; Cordoba J; Dhawan A; Stolze Larsen F; Manns M; Nevesn F; Samuel D; Simpson KJ; Yaron I; Bernardi M. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - STAMPA. - 66:(2017), pp. 1047-1081. [10.1016/j.jhep.2016.12.003]
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.
BERNARDI, MAURO
2017
Abstract
The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. In the context of hepatological practice, however, ALF refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. The disease process is associated with development of a coagulopathy of liver aetiology, and clinically apparent altered level of consciousness due to hepatic encephalopathy. Several important measures are immediately necessary when the patient presents for medical attention. These, as well as additional clinical procedures will be the subject of these clinical practice guidelines.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.