This work was aimed at characterizing and validating a very compact, USB-powered, CdZnTe detector for gamma-ray spectrometry applications in radiopharmacy. A GR1 model (by KromekTM, Sedgefield, UK) was utilized. The detector was calibrated in energy and efficiency.Samples of [18F]FDG and [68Ga]-DOTANOC were measured to assess the detector’s suitability in radionuclidic purity measurements. The energy resolution and the efficiency obtained are fully adequate for quality control of positron emission tomography radiopharmaceuticals. Results of [18F]FDG and [68Ga]-DOTANOC samples proved to be comparable to those obtained using high-purity Germanium detectors. The performance of the detector and its very compact size make this type of device an extremely attractive tool for QC applications in radiopharmacy.
An innovative gamma-ray spectrometry system using a compact and portable CZT detector for radionuclidic purity tests of PET radiopharmaceuticals / Vichi, Sara; Infantino, Angelo; Cicoria, Gianfranco; Pancaldi, Davide; Mostacci, Domiziano; Lodi, Filippo; Marengo, Mario. - In: RADIATION EFFECTS AND DEFECTS IN SOLIDS. - ISSN 1042-0150. - STAMPA. - 171:9-10(2016), pp. 726-735. [10.1080/10420150.2016.1253090]
An innovative gamma-ray spectrometry system using a compact and portable CZT detector for radionuclidic purity tests of PET radiopharmaceuticals
VICHI, SARA;MOSTACCI, DOMIZIANO;MARENGO, MARIO
2016
Abstract
This work was aimed at characterizing and validating a very compact, USB-powered, CdZnTe detector for gamma-ray spectrometry applications in radiopharmacy. A GR1 model (by KromekTM, Sedgefield, UK) was utilized. The detector was calibrated in energy and efficiency.Samples of [18F]FDG and [68Ga]-DOTANOC were measured to assess the detector’s suitability in radionuclidic purity measurements. The energy resolution and the efficiency obtained are fully adequate for quality control of positron emission tomography radiopharmaceuticals. Results of [18F]FDG and [68Ga]-DOTANOC samples proved to be comparable to those obtained using high-purity Germanium detectors. The performance of the detector and its very compact size make this type of device an extremely attractive tool for QC applications in radiopharmacy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
