The preparation of atropisomeric 2,1-borazaronaphthalenes is described. Resolution of the atropisomeric pair was achieved by preparative Chiral Stationary Phase HPLC (CSP-HPLC). The absolute configuration of the stereogenic axis was derived from Time-Dependent DFT (TD-DFT) simulation of the Electronic Circular Dichroism spectra (ECD). X-ray diffraction and Dynamic NMR data allowed structural and dynamic comparison with the analogue isosteric carbon compounds.

Axial Chirality about Boron-Carbon Bond: Atropisomeric Azaborines / Mazzanti, Andrea; Mercanti, Elia; Mancinelli, Michele. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 18:11(2016), pp. 2692-2695. [10.1021/acs.orglett.6b01159]

Axial Chirality about Boron-Carbon Bond: Atropisomeric Azaborines

MAZZANTI, ANDREA;MANCINELLI, MICHELE
2016

Abstract

The preparation of atropisomeric 2,1-borazaronaphthalenes is described. Resolution of the atropisomeric pair was achieved by preparative Chiral Stationary Phase HPLC (CSP-HPLC). The absolute configuration of the stereogenic axis was derived from Time-Dependent DFT (TD-DFT) simulation of the Electronic Circular Dichroism spectra (ECD). X-ray diffraction and Dynamic NMR data allowed structural and dynamic comparison with the analogue isosteric carbon compounds.
2016
Axial Chirality about Boron-Carbon Bond: Atropisomeric Azaborines / Mazzanti, Andrea; Mercanti, Elia; Mancinelli, Michele. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 18:11(2016), pp. 2692-2695. [10.1021/acs.orglett.6b01159]
Mazzanti, Andrea; Mercanti, Elia; Mancinelli, Michele
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/565114
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