Advances in biological techniques have potentiated great progresses in understanding the interaction between human beings and the ∼10 to 100 trillion microbes living in their gastrointestinal tract: gut microbiota (GM). In this review, we describe recent emerging data on the role of GM in hematopoietic stem cell transplantation, with a focus on immunomodulatory properties in the immune system recovery and the impact in the development of the main complications, as GvHD and infections.
Gut microbiota and hematopoietic stem cell transplantation: where do we stand? / Zama, D; Biagi, E; Masetti, R; Gasperini, P; Prete, A; Candela, M; Brigidi, P; Pession, A. - In: BONE MARROW TRANSPLANTATION. - ISSN 1476-5365. - ELETTRONICO. - 52:(2017), pp. 7-14. [10.1038/bmt.2016.173]
Gut microbiota and hematopoietic stem cell transplantation: where do we stand?
ZAMA, DANIELE;BIAGI, ELENA;MASETTI, RICCARDO;GASPERINI, PIETRO;PRETE, ARCANGELO;CANDELA, MARCO;BRIGIDI, PATRIZIA;PESSION, ANDREA
2017
Abstract
Advances in biological techniques have potentiated great progresses in understanding the interaction between human beings and the ∼10 to 100 trillion microbes living in their gastrointestinal tract: gut microbiota (GM). In this review, we describe recent emerging data on the role of GM in hematopoietic stem cell transplantation, with a focus on immunomodulatory properties in the immune system recovery and the impact in the development of the main complications, as GvHD and infections.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
