The synthetic approach to methyl N-(tert-butoxycarbonyl)- S-(3-thienyl)-L-cysteinate (1) and methyl N-(tert-butoxycarbonyl)- S-[2-(3-thienyl)ethyl]-L-cysteinate (2) through tosylate intermediates is reported and discussed. These compounds, which combine the properties of the cysteine side-chain with those of the thiophene ring represent both potential bioactive molecules and interesting synthons for the development of new materials.
Synthesis of two novel cysteine functionalized thiophenes
LANZI, MASSIMILIANO;
2005
Abstract
The synthetic approach to methyl N-(tert-butoxycarbonyl)- S-(3-thienyl)-L-cysteinate (1) and methyl N-(tert-butoxycarbonyl)- S-[2-(3-thienyl)ethyl]-L-cysteinate (2) through tosylate intermediates is reported and discussed. These compounds, which combine the properties of the cysteine side-chain with those of the thiophene ring represent both potential bioactive molecules and interesting synthons for the development of new materials.File in questo prodotto:
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